Table 1 Questions and answer possibilities of the “EXPLORATION” survey
Questions | Answer possibilities |
|---|---|
Q1: What is your critical care background training? | Medical |
Anesthesia | |
Surgical | |
Pediatric | |
Neurology | |
Q2: How long have you been working in critical care? | In training |
Completed training and < 10 years’ clinical experience | |
Completed training and > 10 years’ clinical experience | |
Q3: In which ICU setting do you work? | University hospital ICU |
High-performance non-university hospital ICU | |
Basic care ICU | |
Q4: Do you use in your clinical practice extracorporeal blood purification techniques (aside classical renal replacement therapy) as an adjunctive treatment of sepsis or septic shock? | Yes |
No | |
Q5: How often do you use extracorporeal blood purification techniques a year? | < 5 |
5–10 | |
10–20 | |
> 20 | |
Q6: What is the most common extracorporeal blood purification technique that you use as an adjunctive treatment of sepsis or septic shock? | High-volume hemofiltration |
Cytokine adsorption (Cytosorb) | |
Coupled plasma filtration and adsorption (CPFA) | |
oXIRIS | |
Therapeutic plasma exchange | |
Seraph 100 adsorber | |
High-cut-off dialysis | |
Polymyxin B hemoperfusion (toramycin) | |
Other (please specify): | |
Q7: How good is the theoretical rationale for using extracorporeal blood purification techniques as an adjunctive treatment of sepsis or septic shock? | 1 = very high |
2 = high | |
3 = moderate | |
4 = low | |
5 = very low | |
6 = not existing | |
Q8: How good is the current clinical evidence in general for using extracorporeal blood purification techniques as an adjunctive treatment of sepsis or septic shock? | 1 = very high |
2 = high | |
3 = moderate | |
4 = low | |
5 = very low | |
6 = not existing | |
Q9: What is the extracorporeal blood purification technique with the best evidence endorsing its use as an adjunctive treatment of sepsis or septic shock? | High-volume hemofiltration |
Cytokine adsorption (Cytosorb) | |
Coupled plasma filtration and adsorption (CPFA) | |
oXIRIS | |
Therapeutic plasma exchange | |
Seraph 100 adsorber | |
High-cut-off dialysis | |
Polymyxin B hemoperfusion (toramycin) | |
Other (please specify): | |
Q10: What is the extracorporeal blood purification technique most promising for future use as an adjunctive treatment of sepsis or septic shock, that however needs better evidence from RCTs? | High-volume hemofiltration |
Cytokine adsorption (Cytosorb) | |
Coupled plasma filtration and adsorption (CPFA) | |
oXIRIS | |
Therapeutic plasma exchange | |
Seraph 100 adsorber | |
High-cut-off dialysis | |
Polymyxin B hemoperfusion (toramycin) | |
Other (please specify): |