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Fig. 2 | Intensive Care Medicine Experimental

Fig. 2

From: Recombinant antithrombin attenuates acute kidney injury associated with rhabdomyolysis: an in vivo animal study

Fig. 2

Recombinant antithrombin (rAT) treatment ameliorated acute kidney injury induced by rhabdomyolysis. a–c Serum blood urea nitrogen (a), creatinine (b), and neutrophil gelatinase-associated lipocalin (c) concentrations in mice measured using an enzyme-linked immunosorbent assay (n = 6 in each group). d Hematoxylin and eosin-stained renal tissues, with arrows indicating the loss of tubular epithelial cell nuclei (black arrows), enlarged tubular epithelial cell nuclei (white arrows), and tubular meandering (blue arrows). e Graph showing the histological scores of renal injury (n = 6 in each group). *P < 0.05 vs. sham-operated mice; +P < 0.05 vs. saline-injected mice. Scale bars: 50 µm (d)

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