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Fig. 10 | Intensive Care Medicine Experimental

Fig. 10

From: The impact of ECPELLA on haemodynamics and global oxygen delivery: a comprehensive simulation of biventricular failure

Fig. 10

Impact of ECPELLA on total systemic flow. Data from protocols 1–3 (Figs. 3, 5 and 7) were used. Upper panels represent the impact of VA-ECMO flow changes on total systemic flow in LVF (A), BVF (B), and BVF with PH (C), and the comparison among the three conditions: VA-ECMO + Impella P6, VA-ECMO + Impella P2, and VA-ECMO alone. Lower panels represent the impact of Impella support levels on total systemic flow in LVF (D), BVF (E), and BVF with PH (F), and the comparison among the three conditions: VA-ECMO 4 L/min + Impella, VA-ECMO 2 L/min + Impella, and Impella alone. VA-ECMO markedly increased total systemic flow, and the addition of Impella further increased it. The presence of PH significantly limits the flow-supporting effect of VA-ECMO, Impella and ECPELLA. LVF, left ventricular failure; BVF, biventricular failure; PH, pulmonary hypertension; VA-ECMO, veno-arterial extracorporeal membrane oxygenation

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