Table 2 Results PCV (baseline) vs. optimized FCV (step 3)
From: Flow-controlled ventilation decreases mechanical power in postoperative ICU patients
PCV baseline Median (IQR) | FCV step 3 Median (IQR) | p value | |
|---|---|---|---|
Respiratory parameters | |||
Inspiratory TV/IBW (mL) | 6.0 (5.5–7.1) | 8.4 (7.9–8.7) | 0.004 |
Driving pressure (cmH2O) | 9.2 (7.7–11.7) | 11.9 (9.8–14.0) | 0.031 |
PEEP set (cmH2O) | 7.5 (6.4–8.0) | 8.0 (5.8–8.0) | 1.000 |
PEEP total (cmH2O) | 8.3 (7.5–9.2) | 8.4 (7.5–10.1) | 1.000 |
Ppeak set (cmH2O) | 20.0 (18.8–22.0) | 20.5 (19.8–24.3) | 0.281 |
Ppeak measured (cmH2O) | 18.6 (16.8–21.5) | 21.1 (20.2–24.9) | 0.012 |
Pplat (cmH2O) | 17.5 (16.2–20.5) | 20.0 (19.0–24.0) | 0.011 |
Pmean (cmH2O) | 12.6 (11.0–13.4) | 14.7 (13.0–16.9) | < 0.001 |
Crs static (mL/cmH2O) | 44.5 (36.1–52.7) | 47.0 (39.7–51.8) | 1.000 |
Resistance (cmH2O/L/s) | 13.8 (12.4–14.9) | 8.2 (6.8–9.1) | 0.002 |
RR (x/min) | 18 (17.5–20.0) | 8.5 (7.6–13.1) | < 0.001 |
Minute volume (L/min) | 8.0 (6.5–8.4) | 4.8 (4.4–7.3) | 0.001 |
Mechanical power (J/min) | 11.0 (8.5–12.8) | 7.7 (5.7–11.4) | 0.004 |
Mechanical power, bedside formulas (J/min) | 13.2 (10.5–15.2) | 8.0 (5.9–11.6) | 0.003 |
Dissipated energy (J/L) | 0.34 (0.21–0.43) | 0.20 (0.16–0.27) | 0.009 |
Gas exchange parameters | |||
P/F ratio | 324 (241–365) | 300 (273–369) | 1.000 |
PaO2 (kPa) | 14.3 (12.9–17.7) | 13.1 (12.0–13.9) | 0.212 |
PaCO2 (kPa) | 5.4 (5.1–6.2) | 5.3 (5.1–5.9) | 0.791 |
Ventilatory ratio | 1.20 (1.11–1.31) | 0.75 (0.67–1.15) | 0.001 |
Hemodynamic parameters | |||
Arterial-venous delta CO2 (kPa) | 1.06 (0.86–1.13) | 0.82 (0.77–1.09) | 1.000 |
ScvO2 (%) | 71.2 (64.7–75.8) | 69.1 (64.1–76.0) | 1.000 |
Dose noradrenalin (ug/kg/min) | 0.11 (0.05–0.16) | 0.13 (0.04–0.16) | 1.000 |