Blood flow = 1500 mL/min | Blood flow = 3500 mL/min | |||||||
---|---|---|---|---|---|---|---|---|
Variable | Sweep flow 3.0 L/min | Sweep flow 1.5 L/min | Sweep flow 10 L/min | Sweep flow 2.0 L/min | Sweep flow 3.5 L/min | Sweep flow 7.0 L/min | Sweep flow 12 L/min | P value* |
pH | 7.21 [7.17,7.32] | 7.03 [7.01,7.16] | 7.26 [7.19,7.38] | 7.08 [7.04,7.22] | 7.16 [7.14,7.29] | 7.31 [7.27,7.40] | 7.43 [7.37,7.49] | <0.001 |
SBE (mmol/L) | 0.9 [0.0,1.4] | −5.2 [−9.1,−1.2] | 0.3 [−2.2,2.5] | −0.3 [−1.7,0.4] | 1.2 [−1.2,2.0] | 4.3 [2.9,4.9] | 4.8 [4.7,6.3] | <0.001 |
SatO2 (%) | 87 [81,98] | 85 [75,96] | 97 [80,99] | 99 [91,100] | 99 [91,100] | 99 [96,99] | 99 [98,100] | 0.003 |
CaO2 (mL O2/100 mL of blood) | 17 [14,17] | 16 [13,18] | 17 [14,18] | 15 [14,18] | 17 [15,18] | 15 [15,19] | 15 [14,18] | 0.764 |
CaCO2 (mL CO2/100 mL of blood) | 58 [57,64] | 65 [54,66] | 64 [58,66] | 67 [63,74] | 64 [61,64] | 65 [63,65] | 63 [63,69] | 0.179 |
Lactate (mmol/L) | 1.6 [1.3,2.2] | 2.7 [1.7,3.6] | 1.9 [1.7,4.3] | 2.6 [1.1,3.4] | 1.6 [1.6,3.2] | 1.0 [1.0,1.8] | 1.7 [0.8,2.1] | 0.031 |
Hemoglobin (g/dL) | 13 [12,14] | 14 [13,14] | 13 [12,13] | 12 [11,13] | 12 [12,13] | 12 [11,13] | 11 [10,13] | 0.003 |
Chloride (mmol/L) | 104 [103,104] | 103 [103,104] | 103 [103,104] | 103 [103,104] | 103 [103,104] | 103 [102,105] | 103 [103,104] | 0.880 |
Sodium (mmol/L) | 140 [138,143] | 140 [139,142] | 140 [137,141] | 141 [138,141] | 139 [138,142] | 137 [137,139] | 139 [136,139] | 0.007 |
Calcium (mmol/L) | 1.4 [1.4,1.4] | 1.4 [1.3,1.4] | 1.3 [1.3,1.3] | 1.4 [1.3,1.4] | 1.3 [1.3,1.4] | 1.3 [1.3,1.4] | 1.3 [1.3,1.3] | 0.007 |
Glucose (mg/dL) | 112 [103,131] | 129 [116,214] | 135 [115,158] | 137 [124,138] | 116 [112,127] | 126 [121,128] | 119 [118,121] | 0.007 |
Pulmonary shunt (%) | 47 [26,54] | 60 [33,67] | 45 [29,66] | 67 [55,72] | 54 [47,55] | 56 [31,59] | 50 [44,56] | 0.115 |
Temperature (°C) | 37.2 [36.8,38.5] | 37.5 [36.6,38.4] | 37.5 [36.4,38.2] | 38.0 [37.0,38.1] | 37.7 [36.9,38.2] | 37.5 [37.0,38.2] | 37.5 [37.0,38.2] | 0.534 |
O2 transfer (mL/min) | 116 [108,134] | 115 [103,128] | 133 [98,190] | 246 [211,246] | 201 [197,222] | 206 [200,217] | 207 [181,237] | <0.001 |
CO2 transfer (mL/min) | 209 [204,283] | 185 [178,204] | 319 [275,377] | 255 [223,275] | 259 [238,320] | 365 [294,386] | 383 [296,400] | <0.001 |
Rotations (RPM) | 2075 [1930,2175] | 2075 [1980,2175] | 2075 [1980,2175] | 3485 [3380,3780] | 3485 [3380,3780] | 3485 [3380,3725] | 3485 [3380,3725] | <0.001 |
CO (L/min) | 6.5 [6.4,6.9] | 6.3 [4.0,6.7] | 7.7 [3.6,9.4] | 7.3 [4.3,9.3] | 9.0 [4.4,9.1] | 7.6 [4.8,8.2] | 6.3 [4.8,7.9] | 0.834 |
Heart rate (bpm) | 134 [124,145] | 133 [95,137] | 135 [123,147] | 128 [124,149] | 137 [131,160] | 121 [121,153] | 128 [123,161] | 0.867 |
ABPm (mmHg) | 126 [106,126] | 106 [100,125] | 101 [91,112] | 98 [92,105] | 103 [94,114] | 113 [112,122] | 122 [119,123] | 0.154 |
PAPm (mmHg) | 54 [41,59] | 46 [42,47] | 36 [32,46] | 47 [34,48] | 40 [31,47] | 42 [35,45] | 39 [33,44] | 0.248 |
CVP (mmHg) | 6 [5,13] | 6 [4,16] | 5 [4,13] | 5 [3,15] | 5 [4,14] | 5 [4,11] | 5 [4,11] | 0.299 |
PAOP (mmHg) | 11 [10,12] | 8 [8,11] | 8 [7,11] | 7 [5,9] | 8 [7,8] | 8 [6,16] | 8 [7,17] | 0.715 |