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Table 2 Principal features of monocyte tolerance studies

From: Uncontrolled sepsis: a systematic review of translational immunology studies in intensive care medicine

Author Study population Subjects ( n) Control population Controls ( n) Experimental context Outcome measure correlated with immune readout
Liu [30] Sepsis 2 Healthy volunteer 2 Experimental No
Buttenschoen [41] Elective surgery 20 Cohort 20 Pathophysiological No
Pachot [31] Sepsis 47 Healthy volunteer 21 Pathophysiological Yes
West [32] Sepsis 7 Healthy volunteer, elective surgery and SIRS 16, 5 and 4 Pathophysiological No
Harter [33] Sepsis 21 Healthy volunteer 12 Pathophysiological No
Flohe [40] Surgery in trauma patients 16 Healthy volunteer 12 Pathophysiological No
Escoll [34] Sepsis 3 (5) Healthy volunteer 3 Pathophysiological No
Heagy [39] ICU patients (sepsis) 62 Healthy volunteer 15 Clinical outcome Yes
Calvano [35] Sepsis 18 (10) Healthy volunteer 15 (6) Pathophysiological No
Sfeir [36] Sepsis 10 Healthy volunteer 10 Pathophysiological No
Kawasaki [42] Elective surgery 20 Cohort 20 Pathophysiological No
Heagy [37] Sepsis 58 Healthy volunteer 14 Clinical outcome Yes
Bergmann [38] Sepsis 30 (2) Healthy volunteer 12 Pathophysiological No
  1. Subjects/controls: numbers in brackets refer to subgroups within study.