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An official journal of the European Society of Intensive Care Medicine (ESICM)

Members should contact for a 40% discount on the article-proccessing charge.


  1. Authors: Aleksandra B. Gruslova, Nitesh Katta, Andrew G. Cabe, Scott F. Jenney, Jonathan W. Valvano, Tim B. Phillips, Austin B. McElroy, Robert K. LaSalle, Aydin Zahedivash, Van N. Truskett, Nishi Viswanathan, Marc D. Feldman, Richard B. Wettstein, Thomas E. Milner and Stephen Derdak

    Content type: Research Articles

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  1. Volume 10

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    1. ESICM LIVES 2021 - Part 2

      Volume 10 Supplement 1

      Meeting abstracts

      Virtual. 03-06 October 2021

  2. Volume 9

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    1. ESICM LIVES 2021

      Volume 9 Supplement 1

      Meeting abstracts

      Virtual. 03-06 October 2021

  3. Volume 8

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    1. ESICM LIVES 2020

      Volume 8 Supplement 2

      Meeting abstracts

      Virtual. 06-09 December 2020

    2. The Fourth International Symposium on Acute Pulmonary Injury and Translation Research (INSPIRES IV)

      Volume 8 Supplement 1


      Dresden, Germany. 25-26 November 2019

  4. Volume 7

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    1. ESICM LIVES 2019

      Volume 7 Supplement 3

      Meeting abstracts

      Berlin, Germany. 28 September - 2 October 2019

    2. Sepsis 2019

      Volume 7 Supplement 2

      Meeting abstracts

      Rio de Janerio, Brazil. 09 - 10 May 2019

    3. Proceedings from the Third International Symposium on Acute Pulmonary Injury and Translational Research (INSPIRES III)

      Volume 7 Supplement 1


      Amsterdam, the Netherlands. 4-5 December 2018

  5. Volume 6

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    1. ESICM LIVES 2018

      Volume 6 Supplement 2

      Meeting abstracts

      Paris, France. 20-24 October 2018

    2. Sepsis 2018

      Volume 6 Supplement 1

      Meeting abstracts

      Bangkok, Thailand. 1-3 October 2018

  6. Volume 5

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    1. ESICM LIVES 2017

      Volume 5 Supplement 2

      Meeting abstracts

      Vienna, Austria. September 23-27, 2017

    2. Sepsis 2017 Paris

      Volume 5 Supplement 1

      Meeting abstracts

      Paris, France. September 11 - 13, 2017

  7. Volume 4

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    1. ESICM LIVES 2016

      Volume 4 Supplement 1

      Meeting abstracts

      Milan, Italy. 1-5 October 2016

  8. Volume 3

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    1. ESICM LIVES 2015

      Volume 3 Supplement 1

      Meeting abstracts

      Berlin, Germany. 3-7 October 2015

  9. Volume 2

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    1. ESICM LIVES 2014

      Volume 2 Supplement 1

      Meeting abstracts

      Barcelona, Spain. 27 September - 1 October 2014

New in the pipeline


Thematic Series
Sepsis - what's in the discovery pipeline?


Thematic Series
Gaseous Mediators: Potential application in Critical Care

Thematic Series

Highly accessed papers 2020
Fluids in ARDS: more pros than cons
Pedro L. Silva, et al.
Review  18 December 2020

Method of respiratory rate measurement using a unique wearable platform and an adaptive optical-based approach
Gurpreet Singh, et al.
Research  24 May 2020

Neuromuscular blocking agents in acute respiratory distress syndrome: updated systematic review and meta-analysis of randomized trials
Waleed Alhazzani, et al. for the GUIDE Group
Review  23 October 2020

COVID-19 and VILI: developing a mobile app for measurement of mechanical power at a glance
Angelo Senzi, et al.
Letters to the Editor  09 February 2021

In vitro characterization of PrismaLung+: a novel ECCO2R device
Markus Storr, et al.
Research  13 May 2020

Checkpoint inhibitor therapy in preclinical sepsis models: a systematic review and meta-analysis
Lindsay M. Busch, et al.
Research  04 February 2020

The conundrum of using hyperoxia in COVID-19 treatment strategies: may intermittent therapeutic hyperoxia play a helpful role in the expression of the surface receptors ACE2 and Furin in lung tissue via triggering of HIF-1α?
Andreas Koch, et al.
Hypothesis  15 September 2020

Pathophysiology and clinical consequences of arterial blood gases and pH after cardiac arrest
Chiara Robba, et al.
Review  18 December 2020

Carbon monoxide in intensive care medicine - time to start the therapeutic application?!
Ulrich Goebel & Jakob Wollborn 
Review  09 January 2020

Real-time effects of PEEP and tidal volume on regional ventilation and perfusion in experimental lung injury
João Batista Borges, Federico Formenti, et al.
Research  21 February 2020

Emerging pharmacological tools to control hydrogen sulfide signaling in critical illness
Eizo Marutani & Fumito Ichinose 
Review  31 January 2020

Heart failure supported by veno-arterial extracorporeal membrane oxygenation (ECMO): a systematic review of pre-clinical models
Sacha Rozencwajg, Jacky Suen, et al. on behalf of the European Extracorporeal Life Support Organisation (EuroELSO) Innovations Workgroup & the National Health Medical Research Council Australia Centre of Research Excellence for Advanced Cardio-respiratory Therapies Improving Organ Support (NHMRC CREACTIONS)
Review  25 May 2020

Use of the CytoSorb adsorption device in MDMA intoxication: a first-in-man application and in vitro study
Corinna N. Lang, Achim Lother, et al.
Research  15 June 2020

The surviving sepsis campaign: basic/translational science research priorities
Clifford S. Deutschman, et al. for the Research Committee of the Surviving Sepsis Campaign
Consensus document  17 July 2020

The effect of positive end-expiratory pressure on cardiac output and oxygen delivery during cardiopulmonary resuscitation
Yosef Levenbrown, et al. 
Research 25 July 2020

ESICM meeting abstracts


Article-processing charges

Intensive Care Medicine Experimental levies an article-processing charge of £1570/$2290/€1870 for each article accepted for publication. For information on waivers and discounts, please visit our article-processing charge page.

Intensive Care Medicine


Aims and scope

Intensive Care Medicine Experimental (ICMx) is an open access journal specifically dedicated to translational research, aimed at bringing discoveries, potential novel treatments and improved diagnostics closer to the bedside of a critically ill patient. As such, ICMx is uniquely positioned at the intersection of clinical and basic science with a primary focus on critical care medicine. ICMx is intended for all those involved in research aimed at improving care of the critically ill.
ICMx aims at publishing research aspiring to: 1) advance understanding of mechanisms of critical illness, 2) support or enhance clinical trial design, 3) test experimental novel treatment interventions, 4) develop or refine experimental models that are relevant to critical care conditions.
ICMx welcomes original studies, reviews, hypothesis papers and state-of-the-art methodology papers. We also encourage correspondence pertinent to the works published in ICMx. Editorial comments will be solicited.

  • ICMx is the official journal of the European Society of Intensive Care Medicine that is dedicated to translational research
  • ICMx is one of few journals publishing research constructing the pipeline of novel discoveries that can advance critical care
  • The board of ICMx represents both basic scientists dedicated to ICU medicine and ICU physicians, providing for an ideal platform to bring discoveries to clinical applications in critical care

Nicole Juffermans, Editor-in-Chief

University of Amsterdam, The Netherlands

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Annual Journal Metrics

  • Speed
    42 days to first decision for reviewed manuscripts only
    35 days to first decision for all manuscripts
    76 days from submission to acceptance
    56 days from acceptance to publication

    229 Altmetric Mentions