Table 1
Time | T0 | T0 | T1 | T1 | T2 | T2 | T3 | T3 |
|---|---|---|---|---|---|---|---|---|
Study Group | TH | TH-SNP | TH | TH-SNP | TH | TH-SNP | TH | TH-SNP |
Heart rate, bpm | 73.7 ± 9.3 | 73.5 ± 11.5 | 86.5 ± 7.6 | 89.5 ± 7.4 | 55.8 ± 11.8 | 55.5 ± 6.4 | 83.3 ± 9.8 | 80.6 ± 4.3 |
Mean arterial pressure, mmHg | 113.3 ± 8.4 | 112.0 ± 5.4 | 103.3 ± 8.6 | 94.5 ± 8.4 | 86.8 ± 18.1 | 79.0 ± 9.4 | 82.8 ± 10.3 | 90.3 ± 3.9 |
PPV, % | 86.8 ± 3.4 | 86.5 ± 2.7 | 39.5 ± 12.6$ | 45.3 ± 6.3$ | 39.6 ± 14.2$ | 49.8 ± 13.2$ | 56.3 ± 6.8$ | 65.5 ± 6.7$ |
MFI | 2.8 ± 0.1 | 2.8 ± 0.1 | 1.9 ± 0.1$ | 2.0 ± 0.1$ | 1.7 ± 0.1$ | 1.9 ± 0.2$ | 2.3 ± 0.2$ | 2.7 ± 0.1*$ |
BLD (%/baseline) | 100 | 100 | 42.1 ± 1.9$ | 51.3 ± 3.5$ | 52.8 ± 2.9$ | 53.6 ± 2.5$ | 90.7 ± 0.6$ | 92.5 ± 2.1$ |
LPR | 12.5 ± 1.8 | 13.9 ± 4.1 | 16.3 ± 4.1 | 19.7 ± 1.7 | 31.7 ± 5.4$ | 24.3 ± 3.3$ | 61.1 ± 13.8$ | 40.5 ± 1.3*$ |