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Volume 2 Supplement 1

ESICM LIVES 2014

  • Poster presentation
  • Open Access

0391. Comparison of the histopathologic effects on the lungs of two external chest compression devices (lucas versus autopulse) in a swine model of ventricular fibrillation

  • 1,
  • 1,
  • 1,
  • 1,
  • 1,
  • 1,
  • 1,
  • 1,
  • 2 and
  • 3
Intensive Care Medicine Experimental20142 (Suppl 1) :P24

https://doi.org/10.1186/2197-425X-2-S1-P24

  • Published:

Keywords

  • Lung Injury
  • Ventricular Fibrillation
  • Histopathology Finding
  • Lower Lobe
  • Lung Biopsy

Introduction

Given the difficulty of performing efficient CPR compressions, technology has turned to automaticity. LUCAS device has a pneumatically driven piston to compress the heart and uses active decompression suction on the upstroke. AUTOPULSE is a load distributing band compressor, that is mechanically actuated and battery driven. It provides both direct compression and semi-circumferential thoracic compression.

Objectives

Lung injury may occur during cardiorespiratory resuscitation with external chest compression devices. Aim of this study is to compare 2 different external chest compression devices (LUCAS and AUTOPULSE) regarding differences in lung injury that they may cause.

Methods

Forty (40) pigs were randomly allocated into 2 groups. Group L (LUCAS), n=20 and Group A (AUTOPULSE), n=20. After anesthesia, ventricular fibrillation was induced. Five minutes post-cardiac arrest without treatment, resuscitation was initiated. After resuscitation, lung biopsy via a mini-thoracotomy was obtained (right lung lower lobe).

Results

Histopathology findings revealed a heterogeneous interstitial infiltrate and vascular congestion in all samples studied. There was no statistically significant difference between the two groups. (P>0.05)

Conclusions

LUCAS and AUTOPULSE devices present no histopathological differences concerning lung injury after cardiorespiratory resuscitation.

Authors’ Affiliations

(1)
General Hospital of Athens Laiko, Intensive Care Unit, Athens, Greece
(2)
University of Athens, Medical School, Neonatology, Athens, Greece
(3)
University of Athens, Medical School, M.Sc. Programme in Cardiorespiratory Resuscitation, Athens, Greece

References

  1. Axelsson C, et al.: Clinical consequences of the introduction of mechanical chest compression in the EMS system for treatment of out-of-hospital cardiac arrest-a pilot study. Resuscitation 2006,71(1):47–55. 10.1016/j.resuscitation.2006.02.011PubMedView ArticleGoogle Scholar
  2. Ong ME, et al.: Use of an automated, load-distributing band chest compression device for out-of-hospital cardiac arrest resuscitation. JAMA 2006,295(22):2629–37.PubMedView ArticleGoogle Scholar

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