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Volume 2 Supplement 1


0391. Comparison of the histopathologic effects on the lungs of two external chest compression devices (lucas versus autopulse) in a swine model of ventricular fibrillation


Given the difficulty of performing efficient CPR compressions, technology has turned to automaticity. LUCAS device has a pneumatically driven piston to compress the heart and uses active decompression suction on the upstroke. AUTOPULSE is a load distributing band compressor, that is mechanically actuated and battery driven. It provides both direct compression and semi-circumferential thoracic compression.


Lung injury may occur during cardiorespiratory resuscitation with external chest compression devices. Aim of this study is to compare 2 different external chest compression devices (LUCAS and AUTOPULSE) regarding differences in lung injury that they may cause.


Forty (40) pigs were randomly allocated into 2 groups. Group L (LUCAS), n=20 and Group A (AUTOPULSE), n=20. After anesthesia, ventricular fibrillation was induced. Five minutes post-cardiac arrest without treatment, resuscitation was initiated. After resuscitation, lung biopsy via a mini-thoracotomy was obtained (right lung lower lobe).


Histopathology findings revealed a heterogeneous interstitial infiltrate and vascular congestion in all samples studied. There was no statistically significant difference between the two groups. (P>0.05)


LUCAS and AUTOPULSE devices present no histopathological differences concerning lung injury after cardiorespiratory resuscitation.


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Pantazopoulos, C., Floros, I., Mega, A. et al. 0391. Comparison of the histopathologic effects on the lungs of two external chest compression devices (lucas versus autopulse) in a swine model of ventricular fibrillation. ICMx 2 (Suppl 1), P24 (2014).

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  • Lung Injury
  • Ventricular Fibrillation
  • Histopathology Finding
  • Lower Lobe
  • Lung Biopsy