Skip to main content

Volume 3 Supplement 1


Implementation of a protocol for predicting successful extubation in critically ill patients


Weaning protocols have been show to be better than traditional physician directed discontinuation of mechanical ventilation. Extubation failure can cause increased complications, higher ICU length of stay, higher cost, morbidity and mortality.


The aims of the present study are to analyze the influence of implementation an extubation protocol and to compare clinical outcome with a traditional strategy based in the physician´s criteria for discontinue mechanical ventilation.


Observational study performed in a 17 beds medical-surgical ICU. Time of study was 18 months. Consecutive mechanically ventilated patients during more than 48 hours were included. The variables analyzed were age, sex, cause of the intubation, APACHE II at admission in ICU, vasoactive requirements, fluid balance, day of weaning, ICU length of stay, tracheotomy, rate of reintubation. We distinguish two subgroups according extubation strategy, based in physician´s criteria vs protocol designed by a intensivist and nursing team including haemodynamic and respiratory parameters like: negative inspiratory force, maximal inspiratory pressure, f/VT, airway occlusion pressure at 0,1 second. The data collected were analyzed using SPSS version 22 for Windows.


91 patients were analyzed, 54 were extubated based on the protocol and 37 according physician criteria. There were not differences in clinical characteristics, APACHE score, fluid balance and vasoactive requirements.

Reintubation rate was higher (35.1% vs 5.6%) in not protocolized group with a statistical significant difference (RR, 0.109; 95% CI 0.028-0.417). Tracheotomy requirements, ICU lenght of stay and mortality was lower in the protocol -directed ventilator weaning group.


Physician directed extubation was associated with an increase in the rate of reintubations and ICU length of stay compared with a protocolized weaning strategy.

Table 1 Study characteristics

Author information

Authors and Affiliations


Rights and permissions

Open Access  This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.

The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.

To view a copy of this licence, visit

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Guijo González, P., Estella, Á., Ramos Rodríguez, J. et al. Implementation of a protocol for predicting successful extubation in critically ill patients. ICMx 3 (Suppl 1), A316 (2015).

Download citation

  • Published:

  • DOI: