Skip to main content


Volume 3 Supplement 1


Implementation of a protocol for predicting successful extubation in critically ill patients

Article metrics

  • 281 Accesses


Weaning protocols have been show to be better than traditional physician directed discontinuation of mechanical ventilation. Extubation failure can cause increased complications, higher ICU length of stay, higher cost, morbidity and mortality.


The aims of the present study are to analyze the influence of implementation an extubation protocol and to compare clinical outcome with a traditional strategy based in the physician´s criteria for discontinue mechanical ventilation.


Observational study performed in a 17 beds medical-surgical ICU. Time of study was 18 months. Consecutive mechanically ventilated patients during more than 48 hours were included. The variables analyzed were age, sex, cause of the intubation, APACHE II at admission in ICU, vasoactive requirements, fluid balance, day of weaning, ICU length of stay, tracheotomy, rate of reintubation. We distinguish two subgroups according extubation strategy, based in physician´s criteria vs protocol designed by a intensivist and nursing team including haemodynamic and respiratory parameters like: negative inspiratory force, maximal inspiratory pressure, f/VT, airway occlusion pressure at 0,1 second. The data collected were analyzed using SPSS version 22 for Windows.


91 patients were analyzed, 54 were extubated based on the protocol and 37 according physician criteria. There were not differences in clinical characteristics, APACHE score, fluid balance and vasoactive requirements.

Reintubation rate was higher (35.1% vs 5.6%) in not protocolized group with a statistical significant difference (RR, 0.109; 95% CI 0.028-0.417). Tracheotomy requirements, ICU lenght of stay and mortality was lower in the protocol -directed ventilator weaning group.


Physician directed extubation was associated with an increase in the rate of reintubations and ICU length of stay compared with a protocolized weaning strategy.

Table 1 Study characteristics

Author information

Correspondence to Á Estella.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Guijo González, P., Estella, Á., Ramos Rodríguez, J. et al. Implementation of a protocol for predicting successful extubation in critically ill patients. ICMx 3, A316 (2015) doi:10.1186/2197-425X-3-S1-A316

Download citation


  • Fluid Balance
  • Occlusion Pressure
  • Extubation Failure
  • Maximal Inspiratory Pressure
  • Nursing Team