Skip to main content

Volume 3 Supplement 1


Validation of acute physiology and chronic health evaluation (APACHE) IV score in a korea provincial icus by comparing korean simplified acute physiology score (SAPS) III


The Simplified Acute Physiology Score (SAPS) III has been validated as the Korea SAPSIII model in Korea. However, the Acute Physiology and Chronic Health Evaluation (APACHE) IV model has not yet been validated in Korea provincial intensive care units (ICUs).


The aim of this study was to compare the ability of the APACHE IV with Korean SAPS 3 in predicting hospital mortality in a provincial ICU population.


The study was designed as a prospective cohort study for patients admitted to the nine intensive care units in the four provincial academic medical centers from September 2013 to February 2014. Validation and comparison were conducted to measure discrimination and calibration with using the area under the receiver operating characteristic curve (AUC) and the Hosmer-Lemeshow test, respectively.


Among 733 enrolled patients, 34.4% (252/733) were surgical patients. The hospital mortality was 23.5%. The median APACHE IV score was 71(Standard deviation ± 33.8), and the predicted death rate was 25.6% respectively. The observed hospital mortality was 23.5%. The discriminative powers of two models were similar. The AUCs were 0.753 (95% confidence intervals (CI) : 0.711-0.794) for APAPCH IV and 0.768 (95% CI : 0.727-0.809) for Korean SAPS III respectively. Hosmer-Lemeshow C and H statics showed good calibration for both models, (H = 8.69, p = 0.370; C = 128.17, p = 0.824 for APACHE IV, and H = 8.40, p = 0.396; C = 178.98, p < 0.001 for Korean SAPS III respectively).


For Korea regional ICU patients, the APACHE IV and Korea SAPS III showed good discrimination and good calibration for hospital mortality. Therefore, the APACHE IV prognostic model might be applied to predict mortality in Korea regional ICUs.


  1. So Yeon Lim, et al: Validation of SAPS3 Admission Score and Its Customization for Use in Korean ICU Patients: A Prospective Multicenter Study. Respirology. 2013, 18 (6): 989-995.

    Article  Google Scholar 

  2. Jae Yeol Kim, et al: External Validation of the Acute Physiology and Chronic Health Evaluation II in Korean Intensive Care Units. Yonsei Med J. 2013, 54 (2): 425-431.

    Article  Google Scholar 

  3. Hosmer DW, Lemeshow S: Confidence interval estimates of an index of quality performance based on logistic regression models. Stat Med. 1995, 14: 2161-2172.

    Article  PubMed  CAS  Google Scholar 

  4. Hannah Lee, et al: Validation of the APACHE IV model and its comparison with the APACHE II, SAPS 3, and Korean SAPS 3 models for the prediction of hospital mortality in a Korean surgical intensive care unit. Korean J Anesthesiol. 2014, 67: 115-122.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations



Rights and permissions

Open Access  This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.

The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.

To view a copy of this licence, visit

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Moon, J., Kwon, I., Lee, J. et al. Validation of acute physiology and chronic health evaluation (APACHE) IV score in a korea provincial icus by comparing korean simplified acute physiology score (SAPS) III. ICMx 3 (Suppl 1), A335 (2015).

Download citation

  • Published:

  • DOI: