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Volume 3 Supplement 1

ESICM LIVES 2015

Clinical impact of early bronchoscopy in mechanically ventilated patients with aspiration pneumonia

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Background

A handful of studies have reported that the proper timing of bronchoscopy influences the clinical outcome in mechanically ventilated patients with aspiration pneumonia.

Methods

Mechanically ventilated patients with aspiration pneumonia who received bronchoscopy in a medical intensive care unit at tertiary hospital from March 2003 to December 2013 were retrospectively reviewed. By definition, patients who underwent bronchoscopy within 24 hours after intubation were categorized as the early bronchoscopy group. We compared demographics, clinical parameters, and outcomes, including mortality, between the two groups.

Results

182 patients were included. Compared to the late bronchoscopy group, the early bronchoscopy group (n = 93) showed no significant differences in demographic features, including acute physiology and chronic health evaluation II scores. The early bronchoscopy group showed significantly lower in-ICU mortality and 90-day mortality (in-ICU: 6.5% vs. 26.1%; 90-day: 10.8 vs. 33.0%) regardless of the appropriateness of the initial empirical antibiotics. In addition, their sequential organ failure assessment score on day 7 tended to decrease more rapidly. The early timing of bronchoscopy was associated with a lower 90-day mortality in multivariate analysis (odds ratio: 0.415; 95% confidence interval 0.183-0.942).

Conclusions

Early bronchoscopy could benefit the clinical outcomes of mechanically ventilated patients with aspiration pneumonia.

Author information

Correspondence to S Park.

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0), which permits use, duplication, adaptation, distribution, and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Cite this article

Park, S., Cho, Y. & Lee, Y. Clinical impact of early bronchoscopy in mechanically ventilated patients with aspiration pneumonia. ICMx 3, A388 (2015) doi:10.1186/2197-425X-3-S1-A388

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Keywords

  • Intensive Care Unit
  • Clinical Outcome
  • Organ Failure
  • Clinical Parameter
  • Health Evaluation