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Volume 3 Supplement 1

ESICM LIVES 2015

  • Poster presentation
  • Open Access

Short and Long-Term Outcome of 75 or Over Aged Patients Admitted to Intensive Care Unit (ICU): A Single Center, Observational Study

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Intensive Care Medicine Experimental20153 (Suppl 1) :A528

https://doi.org/10.1186/2197-425X-3-S1-A528

  • Published:

Keywords

  • Intensive Care Unit
  • Mortality Risk
  • Multivariable Analysis
  • Intensive Care Unit Admission
  • Intensive Care Unit Patient

Introduction

Age is considered an independent risk factor for short and long-term mortality of elderly ICU patients, when very elderly (≥85 years) and mid-elderly (75-84 years) populations are compared to young elderly (65-74 years) ones. However, it is not yet clear if this trend remains when very elderly are compared to mid-elderly populations.

Objectives

a) to compare short (ICU and hospital) and long-term (6-months and 1-year) mortality of mid-elderly to very elderly patients and

b) to evaluate the influence of patients' characteristics on mortality.

Methods

Single center, retrospective, observational study in an 8-bed adult general ICU (January 2011-June 2014). Patients ≥75 years were divided into two age-groups, 75-84 and ≥85 years old. Characteristics on ICU admission were recorded. Patients hospitalized ≤48 hours were excluded. ICU, hospital, 6-months and 1-year after hospital discharge mortality were calculated. Univariate analysis for categorical variables was performed using Pearson’s x2 or Fisher test and Student t-test for continuous data. Multivariate analysis of the time to ICU mortality was calculated using Cox regression model and for hospital, 6-months and 1-year mortality using logistic regression analysis. P value < 0.05 was considered significant.

Results

244 patients were included, 195 in the 75-84 and 49 in the ≥85 years group. Mortality rates for the two groups were: ICU, 74/195 (37.9%) vs. 24/49 (49%) (p = 0.08), hospital, 23/121 (19%) vs. 5/25 (20%) (p = 0.90), 6-months, 15/95 (17%) vs. 4/20 (20%) (p = 0.74) and 1-year, 22/80 (27.5%) vs. 7/16 (20%) (p = 0.19), respectively. in multivariable analysis, patients with malignancy as reason for ICU admission had increased ICU mortality risk (HR:1.45; CI 95%, 1.02-2.05; p = 0.03). Patients with higher APACHE II score on ICU admission had more important 1-year mortality risk (OR:1.09; CI 95%, 1.016-1.16; p = 0.015).

Conclusions

More than one third of our ICU patients were mid- or very elderly. No difference was observed between the two age-groups considering short or long-term mortality. Malignancy as a reason for ICU admission and APACHE II score negatively influenced the ICU and 1-year mortality, respectively.

Authors’ Affiliations

(1)
Gennimatas General Hospital,Thessaloniki, Greece, Intensive Care Unit, Thessaloniki, Greece

References

  1. Fuchs L, Novack V, McLennan S, Celi LA, Baufield Y, Park S, et al: Trends in severity of illness on ICU admission and mortality among the elderly. PLoS One. 2014, 9 (4): e93234-10.1371/journal.pone.0093234.PubMedPubMed CentralView ArticleGoogle Scholar
  2. Fuchs L, Chronaki CE, Park S, Novack V, Baumfield Y, Scott D, et al: ICU admission characteristics and mortality rates among elderly and very elderly patients. Intensive Care Med. 2012, 38 (10): 1654-1661. 10.1007/s00134-012-2629-6.PubMedView ArticleGoogle Scholar

Copyright

© Lathyris et al.; 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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