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The role of direct current potentials in assessment of energy metabolism pattern in surgical patients
Intensive Care Medicine Experimental volume 3, Article number: A577 (2015)
Correction of metabolic disorders is an obligatory component in treatment of the majority of the pathological processes, allowing to avoid deterioration of a condition of the patient and accordingly to reduce time of stay in a hospital.
Develop a mode of noninvasive, informative and accessible in practical application the express-test of energy metabolism pattern
The study was performed on 183 patients underwent abdominal surgery (duration 6-9 hours). Were assessed central hemodynamics, gas exchange, temperature and nutrition state for the nutrition support. The nutritional support has based on monitored nutritional status. Depending on energy metabolism pattern defined by biochemical tests, patients were divided on 4 groups: group 1 - enzymic energy metabolism pattern, group 2 - hypoxic energy metabolism pattern, group 3 - substrate energy metabolism pattern, group 4 included the patients with hypermetabolic energy metabolism pattern. The concurrent registration of direct-current potential (DCP) and number of superslow oscillations (SSO) was made in a forehead-palm lead.
The enzymic energy metabolism pattern correspond with zero to 3 SSO and DCP value more than -10 mV; the hypoxic energy metabolism pattern correspond with more than 10 SSO and DCP value more than -15 mV; the substrate energy metabolism pattern correspond with more than 10 SSO and “optimal” DCP value of -15 to -35 mV; the hypermetabolic energy metabolism pattern correspond with more than 18 SSO and DCP value less than -35 mV; optimal (normal) energy metabolism pattern correspond with 4 to 9 SSO and DCP value of -15 to -35 mV.
The DCP monitoring allows to determine the kind of energy metabolism pattern on the basis of number of superslow oscillations of direct current potential during ten minutes and background values of direct-current potential.
Zabolotskikh IB, Musaeva TS, Grigoriev SV: The metabolic responses during postanesthesia recovery after prolonged abdominal surgery under total intravenous anesthesia: A-808. European Journal of Anaesthesiology. 2006, 23 (Supplement 37): 209-
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Zabolotskikh, I., Musaeva, T. & Zybin, K. The role of direct current potentials in assessment of energy metabolism pattern in surgical patients. ICMx 3, A577 (2015). https://doi.org/10.1186/2197-425X-3-S1-A577
- Public Health
- Nutrition State
- Metabolic Disorder
- Pathological Process
- Biochemical Test