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Table 1 Patient Characteristics median [range]

From: Hepatic drug metabolism by CYP2D6 in critically ill adults with AKI: effect of phenotype and AKI severity

  All Patients KDIGO 0 KDIGO 1 KDIGO 2 KDIGO 3
Patient No. 72 14 14 16 28
Patient Age 72 [19-88] 75 [22-88] 72.5 [50-82] 72.5 [59-83] 72 [19-88]
Baseline Serum Creatinine (mmol/L) 86 [34-259] 84 [69-112] 94 [58-162] 90 [61-259] 75 [34-221]
Illness Severity Score SOFA/APACHE II 8 [0-16]/ 20 [5-34] 7 [0-11]/ 18 [5-31] 8 [3-16]/ 18 [9-24] 7.5 [4-14]/ 17.5 [13-25] 10 [3-15]/ 20 [13-34]
Reason for admission Medical/Elective surgery/Emergency surgery 46/11/14 7/2/2 10/2/2 8/6/2 21/1/6
BMI 26.42 [17.3-40.4] 25.1 [19.3-39.8] 25.3 [17.3-37.1] 26.4 [20.1-39.3] 28.5 [17.8-40.4]
CYP2D6 Phenotype PM/IM/IMEM/EM/UEM/Unknown 7/24/2/36/1/2 1/6/0/7/0/0 2/3/0/9/0/0 1/5/1/8/1/0 3/10/1/12/0/2
Serum Creatinine at t = 0 (mmol/L) 178 [62-642] 97 [62-126] 156[66-223] 187 [81-280] 281 [74-642]
Time with AKI (h) [KDIGO 0 excluded] 35.5 [6-192] NA 24 [6-72] 37.5 [6-144] 36 [16-192]