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Intensive Care Medicine Experimental
Figure 3 | Intensive Care Medicine Experimental

Figure 3

From: Calcium desensitisation in late polymicrobial sepsis is associated with loss of vasopressor sensitivity in a murine model

Figure 3

TxA 2 receptor-mediated inhibition of MLCP was attenuated in sepsis. The activity state of MLCP was increased in femoral arteries stimulated with U46619 (0.1 μM) in 5-day CLP mice relative to those in sham mice (indexed by reduction in the ratio of Thr855 phosphorylated to unphosphorylated MYPT on Western blot analysis). *p < 0.05, n = 9 to 12.

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