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Intensive Care Medicine Experimental
Figure 4 | Intensive Care Medicine Experimental

Figure 4

From: Attenuated platelet aggregation in patients with septic shock is independent from the activity state of myosin light chain phosphorylation or a reduction in Rho kinase-dependent inhibition of myosin light chain phosphatase

Figure 4

Platelet aggregation is inversely correlated with illness severity. There was a significant correlation (p < 0.05) between sequential organ failure assessment (SOFA) and acute physiology and chronic health evaluation (APACHE) II scores at the time of blood sampling and platelet aggregation induced by (A, C) ADP (r = −0.51 and −0.36) and (B, D) arachidonic acid (r = −0.41 and −0.47) in whole blood taken from patients with septic shock (n = 26). Note: platelet concentration was not significantly lower in the septic shock patients, and there was no correlation between platelet count and either SOFA or APACHE II score (p > 0.05).

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