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Intensive Care Medicine Experimental
Figure 5 | Intensive Care Medicine Experimental

Figure 5

From: Shape descriptors of the “never resting” microglia in three different acute brain injury models in mice

Figure 5

Quantitative analysis of CD11b+ cells 24 h after acute brain injury. Area (A), perimeter (B), circularity (C), Feret’s diameter (D), aspect ratio (E), and solidity (F) calculated for naïve (striatum and cortex), tMCAo, pMCAo, or TBI mice are shown as box and whiskers with line at mean and min-to-max values. One-way ANOVA followed by Tukey’s multiple comparison test, *p < 0.05, **p < 0.01, and ***p < 0.001, n = 6. The drawings beside the y-axis indicate expected values for each parameter depending on cell shape (ramified vs. ameboid) (A, B, C, D, F) or cell symmetry (E). Frequency distribution plots for individual cells are shown. Dotted lines correspond to the value indicated below each line.

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