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Figure 4 | Intensive Care Medicine Experimental

Figure 4

From: A randomized clinical trial of ascorbic acid in open abdominal aortic aneurysm repair

Figure 4

Endothelial adhesion molecules. (A) Plasma sICAM-1 levels decreased in the placebo group from 245(50) to 162(51) ng/ml and in the ascorbic acid group from 287(79) to 204(52) ng/ml after AAA repair and post-operatively were significantly lower in the placebo group compared to ascorbic acid (p = 0.03). (B) Plasma sVCAM-1 levels did not change after AAA repair. In the placebo group the preoperative level was 1132(427) ng/ml and post-operatively 998(484)ng/ml (p = 0.3). In the ascorbic acid group the preoperative level was 1223(471)ng/ml and postoperatively 1088(505)ng/ml (p = 0.4). There were no differences between groups and any time point. (C) sE-Selectin levels decreased in the placebo group from 35(12) to 25(13)ng/ml (p < 0.001) and in the ascorbic acid group from 37(11) to 26(8)ng/ml (p = 0.002) after AAA repair. There were no differences between groups. (D) sP-Selectin levels decreased in the placebo group from 82(52,88) to 59(52,75)ng/ml (p = 0.001) after AAA repair. In the ascorbic acid group the levels were similar pre- and post-operatively (79(70,95) vs. 69(59,82)ng/ml) (p = 0.4).

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