From: A randomized clinical trial of ascorbic acid in open abdominal aortic aneurysm repair
Placebo group | Ascorbate group | |
---|---|---|
n = 18 | n = 13 | |
Mean (SD), Median (IQR) or n (%) | Mean (SD), Median (IQR) or n (%) | |
Demographics | ||
Age (years) | 70.4 (7.4) | 73.2 (5.9) |
Height (m) | 1.71 (0.09) | 1.71 (0.05) |
Weight (kg) | 77.1 (11.1) | 78.2 (7.7) |
BMI (kgm−2) | 26.4 (3.3) | 26.8 (2.8) |
Gender (% male) | 17 (94%) | 11 (85%) |
Past medical history | ||
IHD | 8 (44%) | 4 (31%) |
Atrial Fibrillation | 0 (0%) | 2 (15%) |
Hypertension | 16 (89%) | 12 (92%) |
Cerebrovascular Disease | 1 (6%) | 1 (8%) |
Cardiovascular risk factors | ||
Smoking | 4 (22%) | 5 (38%) |
Hypercholesterolaemia | 10 (56%) | 6 (46%) |
Hypertension | 16 (89%) | 12 (92%) |
Diabetes | 1 (6%) | 0 (0%) |
Drug history | ||
Statin | 12 (67%) | 9 (69%) |
ACE Inhibitors | 5 (28%) | 3 (23%) |
β Blockers | 7 (39%) | 6 (46%) |
Diuretics | 2 (11%) | 3 (23%) |
Anticoagulants | 5 (28%) | 5 (38%) |
Baseline physiological parameters | ||
Respiratory Rate (min−1) | 14 (12,15) | 12 (12,15) |
Temperature (°C) | 36.6 (0.33) | 36.8 (0.38) |
Heart Rate (min−1) | 63 (10.3) | 60 (13.7) |
Peripheral SBP (mmHg) | 145.2 (24.9) | 150.5 (29.6) |
Peripheral DBP (mmHg) | 77 (12.4) | 76 (11.7) |
Haematological and biochemical indices | ||
Haemoglobin (gdl−1) | 13.7 (1.2) | 13.7 (1.1) |
Leucocyte Count (x109ml−1) | 7.3 (1.7) | 7.3 (1.8) |
Platelet Count (x109ml−1) | 201 (54) | 211 (64) |
Urea (mmoll−1) | 7.8 (2.1) | 6.7 (1.8) |
Creatinine (μmoll−1) | 96 (31) | 101 (30) |
Surgical details | ||
Ischaemic Time (mins) | 60.5 (16.9) | 64.6 (17.6) |