An authentic animal model of the very preterm infant on nasal continuous positive airway pressure

Intensive Care Medicine Experimental

Table 1 NIPPV requirements and respiratory rates

Time	NIPPV used	Set NIPPV rate	Mechanically assisted RR	Spontaneous RR	Total RR
Time	n (%)	(inflations/min) ^a	(breaths/min)	(breaths/min)	(breaths/min)
Initial	10 (100)	30 ± 0	25 ± 9.2	24 ± 24	50 ± 20
Pre-CPAP	10 (100)	30 ± 0	26 ± 8.9	21 ± 31	47 ± 25
15 min post-CPAP	5 (50)	15 ± 14	3.9 ± 5.9^b	39 ± 30	43 ± 30
30 min post-CPAP	6 (60)	23 ± 11	14 ± 14	34 ± 30	48 ± 25
45 min post-CPAP	6 (60)	26 ± 10	14 ± 14	39 ± 32	52 ± 22
60 min post-CPAP	4 (40)	22 ± 20	8.8 ± 16^b	41 ± 30	50 ± 22
90 min post-CPAP	3 (30)	33 ± 6.0	8.9 ± 14	49 ± 30	58 ± 25
120 min post-CPAP	1 (10)	46 ± 0	4.6 ± 15^b	55 ± 21^b	60 ± 20
150 min post-CPAP	2 (20)	31 ± 1.4	4.7 ± 10^b	56 ± 24^b	61 ± 15

Values for NIPPV requirements and respiratory rates at each time point; mean ± SD unless stated. Respiratory rate (RR) counted in a 2-min window; reported values are for all lambs, whether or not receiving NIPPV. See text for definition of mechanically assisted breath. ^aReported value for set NIPPV rate includes only lambs receiving NIPPV. ^bDiffers from pre-CPAP value, P < 0.05, ANOVA with Dunnett’s post hoc test.