Skip to main content
Intensive Care Medicine Experimental

Table 1 In vivo protocol and experimental groups

From: Analysis of the influence of antithrombin on microvascular thrombosis: anti-inflammation is crucial for anticoagulation

Groups

1. dose

2. dose

3. dose

Subcutaneous

Intravenous

Intravenous

Control

NaCl (0.9 %)

NaCl (0.9 %)

NaCl (0.9 %)

AT

NaCl (0.9 %)

NaCl (0.9 %)

AT (250 IU/kg)

TrypAT

NaCl (0.9 %)

NaCl (0.9 %)

TrypAT (250 IU/kg)

Indo

indo (5 mg/kg)

NaCl (0.9 %)

NaCl (0.9 %)

Indo + AT

indo (5 mg/kg)

NaCl (0.9 %)

AT (250 IU/kg)

Heparin

NaCl (0.9 %)

heparin (100 IU/kg)

NaCl (0.9 %)

Heparin + AT

NaCl (0.9 %)

heparin (100 IU/kg)

AT (250 IU/kg)

  1. Flow chart displaying the in vivo protocol for the different experimental groups in C57Bl/6J mice. Before intravital fluorescence microscopy (IVM) and thrombosis induction (TI), anesthetized mice received different applications of the respective substances
  2. AT antithrombin, Indo indomethacin, TrypAT tryptophane49-modified AT
Back to article page