Table 1 Baseline data regarding the four groups
Variable | Vehiclea | Mesenchymal stem cell | Conditioned medium | Fibroblast therapy |
|---|---|---|---|---|
Number of animals injured | 9 | 9 | 9 | 9 |
Number of animals treated | 9/9 | 8/9 | 8/9 | 8/9 |
Animal survival post treatment (%) | 9 (100 %) | 8 (100 %) | 8 (100 %) | 8 (100 %) |
Animal weight (g) | 448 ± 19 | 476 ± 35 | 509 ± 25 | 450 ± 12 |
Duration of injurious ventilation (min) | 108 ± 39 | 120 ± 40 | 131 ± 66 | 101 ± 59 |
Lung compliance pre-injury (ml/mmHg) | 0.78 ± 0.14 | 0.75 ± 0.1 | 0.79 ± 0.14 | 0.74 ± 0.05 |
Lung compliance immediately post-VILI | 0.37 ± 0.5 | 0.4 ± 0.04 | 0.41 ± 0.05 | 0.37 ± 0.03 |
Change in compliance from baseline (%) | 50 ± 7 | 49 ± 4 | 48 ± 5 | 49 ± 5 |