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Table 1 Baseline data regarding the four groups

From: Mesenchymal stromal cells are more effective than the MSC secretome in diminishing injury and enhancing recovery following ventilator-induced lung injury

Variable Vehiclea Mesenchymal stem cell Conditioned medium Fibroblast therapy
Number of animals injured 9 9 9 9
Number of animals treated 9/9 8/9 8/9 8/9
Animal survival post treatment (%) 9 (100 %) 8 (100 %) 8 (100 %) 8 (100 %)
Animal weight (g) 448 ± 19 476 ± 35 509 ± 25 450 ± 12
Duration of injurious ventilation (min) 108 ± 39 120 ± 40 131 ± 66 101 ± 59
Lung compliance pre-injury (ml/mmHg) 0.78 ± 0.14 0.75 ± 0.1 0.79 ± 0.14 0.74 ± 0.05
Lung compliance immediately post-VILI 0.37 ± 0.5 0.4 ± 0.04 0.41 ± 0.05 0.37 ± 0.03
Change in compliance from baseline (%) 50 ± 7 49 ± 4 48 ± 5 49 ± 5
  1. Data are expressed as mean ± SD
  2. VILI ventilation-induced lung injury
  3. aTreatment with vehicle alone