Table 1 Hemodynamic data and organ injury in low tidal volume (LVt) versus airway pressure release ventilation (APRV)

MAP

LVt

123.7 ± 15.8

73.3 ± 3.3

77.7 ± 2.7

76.3 ± 4.3

71.3 ± 3.3

0.0811

(mmHg)

APRV

109.3 ± 5.2

86.7 ± 3.9

69.0 ± 1.2

73.0 ± 1.2

72.7 ± 1.5

Cardiac index

LVt

3.2 ± 0.6

2.6 ± 0.3

2.4 ± 0.2

3.7 ± 0.4

3.3 ± 0.7

0.8551

(L min⁻¹ m⁻²)

APRV

2.8 ± 0.5

2.0 ± 0.1

2.1 ± 0.1

2.5 ± 0.3

2.0 ± 0.3

Global end-diastolic index

LVt

596.0 ± 78.0

528.0 ± 139.9

467.7 ± 135.3

543.0 ± 145.0

563.7 ± 167.8

0.0604

(mL min⁻²)

APRV

475.7 ± 141.9

484.7 ± 146.5

407.0 ± 129.0

391.3 ± 116.4

314.0 ± 111.9

Intra-abdominal pressure

LVt

2.3 ± 1.6

13.6 ± 2.4

11.8 ± 2.0

13.1 ± 4.5

11.3 ± 5.0

<0.0001

(cmH₂O)

APRV

0.9 ± 0.5

15.0 ± 2.1

19.5 ± 2.4

25.8 ± 8.5

21.8 ± 0.8

Cumulative urine output (L)

LVt

0.8 ± 0.7

3.8 ± 0.9

6.2 ± 1.2

9.1 ± 1.2

16.7 ± 5.0

0.599

APRV

0.5 ± 0.2

2.4 ± 0.4

4.6 ± 0.7

7.3 ± 0.8

9.1 ± 1.1

Urine output (mL kg⁻¹)

LVt

22.2 ± 18.2

6.4 ± 2.0

5.0 ± 1.5

6.3 ± 1.1

12.2 ± 6.9

0.5469

APRV

14.4 ± 4.0

4.0 ± 1.4

6.8 ± 1.3

4.9 ± 0.6

2.5 ± 0.5

Cumulative fluids administered (L)

LVt

2.1 ± 0.3

11.9 ± 1.7

19.2 ± 2.9

25.7 ± 3.9

36.0 ± 7.5

0.3266

APRV

1.5 ± 0.1

14.3 ± 0.5

22.9 ± 0.5

32.5 ± 0.7

47.8 ± 7.2

Blood urea nitrogen

LVt

5.0 ± 0.4

7.3 ± 1.2

8.7 ± 2.4

9.1 ± 2.7

7.7 ± 1.9

0.9543

(mg dL⁻¹)

APRV

5.7 ± 0.5

7.0 ± 0.5

9.2 ± 0.8

11.8 ± 1.2

11.1 ± 2.8