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Table 1 Hemodynamic data and organ injury in low tidal volume (LVt) versus airway pressure release ventilation (APRV)

From: The effects of airway pressure release ventilation on respiratory mechanics in extrapulmonary lung injury

   Baseline 12 h 24 h 36 h 48 h p value
MAP LVt 123.7 ± 15.8 73.3 ± 3.3 77.7 ± 2.7 76.3 ± 4.3 71.3 ± 3.3 0.0811
(mmHg) APRV 109.3 ± 5.2 86.7 ± 3.9 69.0 ± 1.2 73.0 ± 1.2 72.7 ± 1.5
Cardiac index LVt 3.2 ± 0.6 2.6 ± 0.3 2.4 ± 0.2 3.7 ± 0.4 3.3 ± 0.7 0.8551
(L min−1 m−2) APRV 2.8 ± 0.5 2.0 ± 0.1 2.1 ± 0.1 2.5 ± 0.3 2.0 ± 0.3
Global end-diastolic index LVt 596.0 ± 78.0 528.0 ± 139.9 467.7 ± 135.3 543.0 ± 145.0 563.7 ± 167.8 0.0604
(mL min−2) APRV 475.7 ± 141.9 484.7 ± 146.5 407.0 ± 129.0 391.3 ± 116.4 314.0 ± 111.9
Intra-abdominal pressure LVt 2.3 ± 1.6 13.6 ± 2.4 11.8 ± 2.0 13.1 ± 4.5 11.3 ± 5.0 <0.0001
(cmH2O) APRV 0.9 ± 0.5 15.0 ± 2.1 19.5 ± 2.4 25.8 ± 8.5 21.8 ± 0.8
Cumulative urine output (L) LVt 0.8 ± 0.7 3.8 ± 0.9 6.2 ± 1.2 9.1 ± 1.2 16.7 ± 5.0 0.599
APRV 0.5 ± 0.2 2.4 ± 0.4 4.6 ± 0.7 7.3 ± 0.8 9.1 ± 1.1
Urine output (mL kg−1) LVt 22.2 ± 18.2 6.4 ± 2.0 5.0 ± 1.5 6.3 ± 1.1 12.2 ± 6.9 0.5469
APRV 14.4 ± 4.0 4.0 ± 1.4 6.8 ± 1.3 4.9 ± 0.6 2.5 ± 0.5
Cumulative fluids administered (L) LVt 2.1 ± 0.3 11.9 ± 1.7 19.2 ± 2.9 25.7 ± 3.9 36.0 ± 7.5 0.3266
APRV 1.5 ± 0.1 14.3 ± 0.5 22.9 ± 0.5 32.5 ± 0.7 47.8 ± 7.2
Blood urea nitrogen LVt 5.0 ± 0.4 7.3 ± 1.2 8.7 ± 2.4 9.1 ± 2.7 7.7 ± 1.9 0.9543
(mg dL−1) APRV 5.7 ± 0.5 7.0 ± 0.5 9.2 ± 0.8 11.8 ± 1.2 11.1 ± 2.8
  1. Only intra-abdominal pressure was significant between groups over time; however, there was no significant difference at any individual time point