Table 1 Patient demographics and clinical characteristics
From: Transcriptional reprogramming of metabolic pathways in critically ill patients
Sepsis | SIRS | Healthy controls | |
|---|---|---|---|
Demographics | |||
Number in group | 35 | 12 | 18 |
Mean age (year) | 64 | 61 | 43 |
Severity of illness | |||
Mortality (%) | 26 | 0 | 0 |
Mean APACHE II | 20 | 16 | NA |
Vasopressor support (%) | 72 | 16.8 | 0 |
Renal support (dialysis) (%) | 26 | 8.3 | 0 |
Mechanical ventilation (%) | 78 | 75 | 0 |
Presentation (n)a | |||
Pulmonary infection | 17 | 0 | 0 |
Urinary tract infection | 4 | 0 | 0 |
Abdominal sepsis | 6 | 0 | 0 |
Septicaemia | 3 | 0 | 0 |
Soft tissue infection | 3 | 0 | 0 |
Infective endocarditis | 2 | 0 | 0 |
Post emergency surgery | 7 | 1 | 0 |
Trauma | 1 | 1 | 0 |
Myocardial infarction | 0 | 3 | 0 |
Severe pancreatitis | 0 | 1 | 0 |
Acute pulmonary oedema | 0 | 2 | 0 |
Acute haemorrhage | 0 | 2 | 0 |
Liver failure | 0 | 1 | 0 |
Cardiogenic shock | 0 | 2 | 0 |
Arrhythmias | 0 | 2 | 0 |
Cerebral infarction | 0 | 2 | 0 |
Pre-existing illness (n)a | |||
Hypertension | 9 | 7 | 3 |
Ischaemic heart disease | 9 | 4 | 0 |
Chronic lung disease | 8 | 2 | 0 |
Cancer | 6 | 0 | 0 |
Diabetes | 7 | 3 | 0 |