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Fig. 2 | Intensive Care Medicine Experimental

Fig. 2

From: Sepsis modeling in mice: ligation length is a major severity factor in cecal ligation and puncture

Fig. 2

Survival following ligation of 5 % (n = 10), 20 % (n = 17), and 100 % (n = 10) of total cecal length within 96 h after CLP procedure. At 24 h, survival was 100 % for the 5 % group, 70 % for 20 % group, and 40 % for 100 % group (log-rank test, p < 0.05). At 96 h, we observed 100 % mortality in the 100 % ligated group, 88 % mortality in the 20 % ligated group, and 20 % mortality in the 5 % ligated group (log-rank test, p < 0.0001). The median survival time was 24 h for the 100 % ligated group and 44 h for the 20 % group. The median survival of the 5 % ligated group could not be determined because of the low number of deaths at the end of the observation period (80 % of survival)

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