Known allergy to furosemide or sulphonamides | |
Known pre-hospitalization advanced chronic kidney disease. (eGFR < 30 mL/minute/1.73 m2 or chronic RRT) | |
Severe hypoxic respiratory failure (use of invasive ventilation and FiO2 > 80 % and PEEP > 10 cm H2O) | |
Severe burn injury (≥10 % TBSA) | |
Severe dysnatremia (<120 or > 155 mmol/l) | |
Hepatic coma | |
Mentally disabled undergoing forced treatment. | |
Pregnancy/breast feeding | |
Lack of commitment for on-going life support including RRT | |
Lack of informed consent |