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Table 54 (abstract A1004). Microbiology studies

From: ESICM LIVES 2016: part three

 

Control (4 Animals)

Nebulized Amikacin/Fosfomycin (4 Animals

Nebulized Amikacin (3 Animals)

Nebulized Fosftomycin (4 Animals)

Nebulized Amikacin/Fosfomycin and IV Meropenem (6 Animals)

IV Meropenem (3 Animals)

P-Value

Tracheal Secretions P.aeruginosa Concentration (log cfg/mL)

5.9 ± 1.9

2.9 ± 3.0*

2.4 ± 2.7*

4.7 ± 0.9

2.5 ± 2.8*

5.1 ± 0.9

<0.001

Pulmonary P.aeruginosa Concentration (log cfg/gr)

6.2 ± 1.6

6.3 ± 1.3

6.3 ± 1.0

5.0 ± 2.4

3.8 ± 2.1**

5.3 ± 0.7

<0.001

  1. Data are reported as mean ± SD
  2. IV intravenous
  3. *p < 0.05 vs. Fosfomycin, control and IV meropenem group
  4. **p < 0.05 vs. Amikacin/Fosfomycin, Amikacin and control group