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Fig. 2 | Intensive Care Medicine Experimental

Fig. 2

From: Exploring alternative routes for oxygen administration

Fig. 2

Effects of the administration of pure O2 gas into the bowel on oxygenation and hemodynamics in hypoxemic rats. Breathing 0.1 FiO2, rats were injected with pure O2 gas (15 ml/kg as a bolus followed by a continuous infusion of 50 ml/kg/h for 2 h) into the jejunum (bowel O2 group, n = 8). No oxygen treatment was given to a group of controls (n = 8). Five animals per group were monitored for a further 2 h after infusion discontinuation. Arterial O2 tension (PO2), arterial and central venous O2 saturation (SO2), liver tissue PO2, mean arterial pressure, heart rate, stroke volume, arterial base excess (ABE), and lactate are expressed as mean ± standard error. Muscle tPO2 is expressed as median [first to third quartile]. *p < 0.05, **p < 0.01, and ***p < 0.001 versus baseline in the bowel O2 group; # p < 0.05, ## p < 0.01, and ### p < 0.001 versus baseline in the control group (repeated measure two-way analysis of variance with Bonferroni’s post hoc test or Friedman test with Dunn’s post hoc test)

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