Fig. 5

Reduced liver injury in HDC^−/− mice following CLP-induced sepsis. a, b Serum levels of AST and ALT. Blood samples were collected from sham-operated and CLP-induced septic mice 18 h after surgery (n = 4–11/group). All values are provided as means ± SEM. ***P < 0.001 vs. the respective control (18 h after sham operation). ^## P < 0.01 vs. CLP WT. c, d Representative micrographs liver sections stained with hematoxylin and eosin and anti-MPO antibody followed by peroxidase staining. Original magnification, ×200. Tissues were harvested from sham-operated and CLP-induced septic mice 24 h after surgery. The same results were obtained with two other experiments