Fig. 3

Granulocyte and monocyte adsorptive apheresis (GMA) ameliorated CLP-induced sepsis. a Survival was plotted for a 7-day period (n = 22–25 per group). b Serum inflammatory-associated cytokines were measured by ELISA at 48 h after CLP (n = 6–7 per group). c Serum ALT and AST were quantified at 48 h after CLP (n = 6–7 per group). d, f Representative photomicrographs of liver sections stained with hematoxylin and eosin (HE) and examined at ×100 magnification and of kidney sections stained with HE and examined at ×200 magnification. e, g Histopathologic mean liver and lung injury were scored at 48 h after CLP (n = 6 per group; at least 10 fields were reviewed for each slide). *p < 0.05, **p < 0.01. Data are expressed as mean ± SEM. CLP cecal ligation and puncture, ALT alanine aminotransferase, AST aspartate aminotransferase, ELISA enzyme-linked immunosorbent assay