Table 1 Physiological data
From: Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock
Normo. Sham (n = 6) | Normo. CLP (n = 6) | Hyper. Sham (n = 6) | Hyper. CLP (n = 5) | p value | |
|---|---|---|---|---|---|
NoA (ng/(g · h)) | 0 (0; 0) | 20 (10; 30) | 0 (0; 0) | 30 (20; 100)b, c | 0.001 |
HR (beats/min) | 310 (310; 315) | 481 (397; 503)b | 420 (380; 450)a | 479 (459; 492)c | 0.002 |
MAP (mmHg) | 60 (58; 66) | 60 (56; 62) | 69 (68; 73) | 58 (57; 58) | 0.026 |
Portal ven. flow (ml/min) | 4.3 (3.4; 4.7) | 6.1 (4.5; 11.0) | 4.8 (3.4; 5.8) | 6.2 (5.2; 7.3) | 0.066 |
Liver μ-vasc. flow (AU) | 122 (109; 127) | 111 (93; 176) | 132 (120; 148) | 133 (105; 147) | 0.767 |
Liver μ-vasc. O2 sat. (%) | 61 (58; 63) | 61 (58; 64) | 64 (60; 66) | 65 (60; 66) | 0.481 |
BE (mmol/l) | −7.5 (−10.8; −5.1) | −12.9 (−14.4; −10.9) | −8.2 (−11.0; −7.6) | −13.1 (−13.9; −12.8) | 0.067 |
Lactate (mmol/l) | 1.1 (0.9; 1.4) | 2.1 (1.8; 2.3) | 2.1 (1.7; 2.5) | 3.5 (3.4; 3.6)a, b, c | 0.002 |
VCO2 (μl/(g · min)) | 20.5 (20.2; 20.6) | 25.0 (23.2; 26.6) | 30.4 (29.0; 33.1)a | 26.4 (23.4; 38.9) | 0.031 |
pH | 7.45 (7.38; 7.47) | 7.28 (7.23; 7.39) | 7.35 (7.30; 7.37) | 7.25 (7.16; 7.31) | 0.112 |