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Table 1 Characteristics of ARDS patients and controls of the discovery study

From: A vascular endothelial growth factor receptor gene variant is associated with susceptibility to acute respiratory distress syndrome

Characteristics Cases (n = 225) Controls (n = 889)
Gender (% male) 37 41
Mean age (years) (P25P75) 63 (54–75) 41 (32–49)
Hypertension (%) 44 3
Smoker (%) 30 49
Previous surgery (%) 53 NA
Ischemic cardiac disease (%) 11 NA
Source of sepsis (%)
 Pulmonary 49 NA
 Extrapulmonary 51 NA
Pathogen (%)
 Gram-negative 49 NA
 Gram-positive 33 NA
 Gram-negative and Gram-positive 5 NA
 Polymicrobial 2 NA
 Virus 6 NA
 Fungi 3 NA
Organ dysfunction (%)
 Circulatory 62 NA
 Renal 42 NA
 Hepatic 18 NA
 Neurologic 22 NA
 Coagulation 22 NA
APACHE II (median) (P25P75) 22 (18–27) NA
ICU mortality (%) 44 NA
  1. APACHE II Acute Physiology and Chronic Health Evaluation II, ARDS acute respiratory distress syndrome, ICU intensive care unit, P25 percentile 25, P75 percentile 75, NA not available