Table 1 Characteristics of ARDS patients and controls of the discovery study
Characteristics | Cases (n = 225) | Controls (n = 889) |
|---|---|---|
Gender (% male) | 37 | 41 |
Mean age (years) (P25–P75) | 63 (54–75) | 41 (32–49) |
Hypertension (%) | 44 | 3 |
Smoker (%) | 30 | 49 |
Previous surgery (%) | 53 | NA |
Ischemic cardiac disease (%) | 11 | NA |
Source of sepsis (%) | ||
Pulmonary | 49 | NA |
Extrapulmonary | 51 | NA |
Pathogen (%) | ||
Gram-negative | 49 | NA |
Gram-positive | 33 | NA |
Gram-negative and Gram-positive | 5 | NA |
Polymicrobial | 2 | NA |
Virus | 6 | NA |
Fungi | 3 | NA |
Organ dysfunction (%) | ||
Circulatory | 62 | NA |
Renal | 42 | NA |
Hepatic | 18 | NA |
Neurologic | 22 | NA |
Coagulation | 22 | NA |
APACHE II (median) (P25–P75) | 22 (18–27) | NA |
ICU mortality (%) | 44 | NA |