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Table 2 Shows total particle count for the different particle sizes from 1 to 8 during ex vivo ventilation.

From: A new way of monitoring mechanical ventilation by measurement of particle flow from the airways using Pexa method in vivo and during ex vivo lung perfusion in DCD lung transplantation

  Ex vivo lung perfusion
VCV versus PVC Small tidal volumes versus large tidal volumes Low PEEP versus high PEEP
VCV1 PCV1 p value VCV2 p value PCV2 PCV3 p value
Particle 1 141,087 ± 36,170 51,135 ± 31,907 0.020* 224,313 ± 94,259 0.018* 177,117 ± 41,998 23,258 ± 5060 0.020*
Particle 2 150,750 ± 208 57,818 ± 33,823 0.022* 239,288 ± 95,435 0.026* 222,225 ± 56,596 23,913 ± 5575 0.025*
Particle 3 192,577 ± 46,145 76,725 ± 41,409 0.014* 316,550 ± 120,963 0.028* 308,437 ± 80,941 34,092 ± 8124 0.027*
Particle 4 106,700 ± 35,066 43,818 ± 21,247 0.021* 168,932 ± 63,215 0.028* 186,240 ± 49,551 19,900 ± 4730 0.029*
Particle 5 35,373 ± 12,136 14,056 ± 6778 0.020* 54,517 ± 21,202 0.034* 60,478 ± 19,729 8052 ± 2514 0.032*
Particle 6 23,542 ± 8709 7657 ± 3532 0.034* 33,600 ± 12,443 0.048* 35,550 ± 12,188 5486 ± 1543 0.038*
Particle 7 7070 ± 2883 2388 ± 1097 n.s. 10,107 ± 3723 n.s. 8497 ± 2997 2018 ± 538 0.536
Particle 8 3340 ± 1282 722 ± 222 n.s. 3757 ± 1354 n.s. 3000 ± 977 790 ± 262 0.045*
  1. VCV1 volume-controlled ventilation with small tidal volumes and PEEP at 2, VCV2 volume-controlled ventilation with large tidal volumes and PEEP at 2, PCV1 pressure-controlled ventilation with small tidal volumes and PEEP at 2, PCV2 pressure controlled ventilation with large tidal volumes and PEEP at 2, PCV3 pressure-controlled ventilation with big tidal volumes and PEEP at 10
  2. Significance was defined as: p < 0.05 (*), and p > 0.05 (not significant, n.s.)