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Table 1 Plasma alanine amino transferase (ALT), and lactic acid in control and CLP groups over time. Results are means ± SEM

From: Time course of liver mitochondrial function and intrinsic changes in oxidative phosphorylation in a rat model of sepsis

  6 h 24 h 36 h
CLP Sham CLP Sham CLP Sham
ALT U/L 88.20 ± 9.88* 42.75 ± 5.94 172.60 ± 21.70*‡ 43.00 ± 1.58 129.75 ± 15.93* 39.20 ± 2.59
Lactic acid mmol/L 4.25 ± 0.60 2.21 ± 0.53 6.29 ± 1.09* 2.71 ± 0.95 4.43 ± 0.73* 1.83 ± 0.34
  1. *p < 0.05 compared with matching sham-operated control group; &p < 0.05 compared 24 and 36H CLP; ‡p < 0.05 compared 24 and 6H CLP, from 6 animals per group determined by surgical procedure and following period (6, 24, 36 h)