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Intensive Care Medicine Experimental
Fig. 2 | Intensive Care Medicine Experimental

Fig. 2

From: Cystathionine-γ-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis

Fig. 2

Parameters of kidney function. a Physiological parameters: urine output, plasma creatinine (Creatinine), creatinine clearance (CrCl), and renal venous neutrophil gelatinase-associated lipocalin (NGAL) (all values sham n = 5, sepsis n = 8). b Kidney mitochondrial respiratory activity (sham n = 3, sepsis n = 5). jO2, oxygen consumption; CI, mitochondrial respiratory activity in the coupled state stimulated with complex I substrates and ADP; OxPhos, maximum mitochondrial respiratory activity in the coupled state with complex I and II substrates, fatty acids, and ADP; Olg, leak respiration after inhibition of ATP-synthase with oligomycin; ETS, maximum mitochondrial respiratory activity after uncoupling with FCCP; CII, uncoupled mitochondrial respiratory activity linked to complex II after inhibition of complex I by rotenone. c Plotting of CrCl and mitochondrial activity to noradrenaline infusion (NoA). *p < 0.05; **p < 0.01; n.s. p > 0.05

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