Table 2 Multivariate logistic regression analysis of the association of plasma GPC 1, 3, and 4 with the presence of organ failure and progression to organ failure
From: Elevated plasma glypicans are associated with organ failure in patients with infection
Dependent variable | Independent variables in final model | Variable of interest | Coeff. | Odds ratio | 95% confidence intervals | p value |
|---|---|---|---|---|---|---|
Any organ failure | GPC1 + WBC + CRP + IL-6 + Gram positive | GPC 1 | 0.0631 | 1.065 | 1.032–1.103 | < 0.001 |
GPC3 + IL.6 + PCT + Virus | GPC 3 | 0.584 | 1.790 | 1.215–2.727 | 0.004 | |
GPC4 + temp + Lactate + PCT | GPC 4 | 0.368 | 1.445 | 1.171–1.858 | 0.002 | |
Development of organ failure | GPC1 + temp + CRP + IL.6 + Gram Positive | GPC 1 | 0.0678 | 1.070 | 1.021–1.129 | 0.008 |
GPC3 + PCT + Gram Positive + Virus | GPC 3 | 0.645 | 1.906 | 1.219–3.089 | 0.005 | |
GPC4 + temp + Lactate | GPC 4 | 0.332 | 1.393 | 1.147–1.842 | 0.006 |