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Table 1 Demographic, clinical, and hemodynamic characteristics of the septic patient cohort stratified by their pulse wave velocity quartile

From: Association between increased arterial stiffness and clinical outcomes in patients with early sepsis: a prospective observational cohort study

 

Total

Pulse wave velocity

< 8.1 m/s

8.1–14.6 m/s

14.6–24.7 m/s

> 24.7 m/s

(n = 45)

(n = 12)

(n = 11)

(n = 10)

(n = 12)

Demographic characteristics

 Age (in years)

67 (54–75)

61 (43–73)

57 (49–68)

69 (57–79)

59 (39–78)

 Gender (females), n (%)

17 (38%)

5 (42%)

4 (36%)

5 (50%)

3 (25%)

Clinical characteristics

 APACHE II score

19 (15–25)

21 (14–26)

19 (16–24)

16 (11–19)

19 (15–27)

 SOFA score

7 (4–10)

9 (4–10)

8 (5–9)

4 (3–7)

7 (5–11)

 CV SOFA

3 (0–3)

1 (0–3)

3(1–3)

0 (0–3)

3 (1–4)

 Ventilated, n (%)

18 (40%)

6 (50%)

3 (27%)

1 (10%)

8(67%)

 Septic shock, n (%)

25 (56%)

7 (58%)

6 (55%)

4 (40%)

8 (67%)

 Smoker, n (%)

18 (40%)

6 (50%)

4 (36%)

3 (30%)

5 (40%)

 History of hypertension

21 (47%)

5 (42%)

7 (64%)

6 (56%)

3 (25%)

 History of diabetes

5 (11%)

3 (25%)

1 (13%)

1 (11%)

0

 Established CAD

3 (7%)

2 (17%)

1 (9%)

0

0

Hemodynamic characteristics

 Systolic blood pressure (mm Hg)

110 (97–121)

113 (107–120)

101 (95–116)

107 (90–128)

108 (97–121)

 Mean blood pressure (mmHg)

78 (70–87)

80 (77–85)

75 (70–82)

77 (70–92)

72 (70–82)

 Pulse pressure (mmHg)

47 (36–56)

51 (41–53)

48 (34–58)

44 (34–57)

44 (36–56)

 Diastolic blood pressure (mmHg)

62 (56–71)

62 (60–71)

66 (55–67)

65 (60–78)

58 (44–66)*

 Dose of noradrenaline (mcg/kg/min)

0.03 (0–0.1)

0.03 (0–0.09)

0.03 (0–0.08)

0 (0–0.02)

0.1 (0–0.14)

 Heart rate (beats/min)

90 (82–98)

86 (82–94)

91 (87–101)

85 (64–93)

95 (82–98)

  1. Values are given as median (interquartile range) or number (percentage)
  2. CV SOFA cardiovascular component of SOFA, Established CAD previous myocardial infarction, percutaneous coronary intervention or coronary artery bypass grafting
  3. *Significant at the 0.05 probability level