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Table 1 Staging of AKI [2]

From: Extracellular vesicles as regulators of kidney function and disease

Stage sCr Urine output
1 ▪ 1.5–1.9 times baseline, or
▪ ≥ 0.3 mg/dL (≥ 26.5 mmol/L) increase
< 0.5 mL/kg/h for 6–12 h
2 2.0–2.9 times baseline < 0.5 mL/kg/h for ≥ 12 h
3 ▪ ≥ 3.0 times baseline, or
▪ increase to ≥ 4.0 mg/dL (≥ 353.6 mmol/L), or
▪ initiation of renal replacement therapy, or
▪ in patients < 18 years, decrease in eGFR to
< 35 mL/min per 1.73 m2
▪ < 0.3 mL/kg/h for ≥ 24 h, or
▪ anuria for ≥ 12 h
  1. eGFR estimated glomerular filtration rate. Modified from “KDIGO Clinical Practice Guideline for Acute Kidney Injury”