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Table 1 Staging of AKI [2]

From: Extracellular vesicles as regulators of kidney function and disease

Stage

sCr

Urine output

1

▪ 1.5–1.9 times baseline, or

▪ ≥ 0.3 mg/dL (≥ 26.5 mmol/L) increase

< 0.5 mL/kg/h for 6–12 h

2

2.0–2.9 times baseline

< 0.5 mL/kg/h for ≥ 12 h

3

▪ ≥ 3.0 times baseline, or

▪ increase to ≥ 4.0 mg/dL (≥ 353.6 mmol/L), or

▪ initiation of renal replacement therapy, or

▪ in patients < 18 years, decrease in eGFR to

< 35 mL/min per 1.73 m2

▪ < 0.3 mL/kg/h for ≥ 24 h, or

▪ anuria for ≥ 12 h

  1. eGFR estimated glomerular filtration rate. Modified from “KDIGO Clinical Practice Guideline for Acute Kidney Injury”