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Intensive Care Medicine Experimental
Fig. 1 | Intensive Care Medicine Experimental

Fig. 1

From: Hydrocortisone decreases lethality and inflammatory cytokine and nitric oxide production in rats challenged with B. anthracis cell wall peptidoglycan

Fig. 1

This figure compares proportional survival and mean (± sem) serial changes in mean arterial blood pressure (MBP) and heart rate (HR) during and after a 24-h B. anthracis peptidoglycan infusion (PGN, horizontal arrows) in diluent (control) treated animals versus animals treated with either a high (125 mg/kg) (a), medium (12.5 mg/kg) (b) or low (1.25 mg/kg) (c) dose of hydrocortisone (HC). Hydrocortisone or diluent treatment were administered intravenously 6 h before and at the start of PGN infusion (inverted dark arrow heads). Survival is shown from the start of PGN and serial changes in MBP and HR were measured and shown from 6 h before until either 24 h (high-dose HC) or 48 h (medium and low-dose HC) after the start of PGN

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