Table 1 Subject demographics and clinical data
Variable | COVID19 + patients | COVID19– patients | p-value |
|---|---|---|---|
n | 7 | 7 | 1.000 |
Age in years | 60.0 (56.0, 67.0) | 60.0 (53.0, 63.0) | 0.520 |
Sex | 5F:2 M | 5F:2 M | 1.000 |
MODS | 4.0 (1.0, 7.0) | 5.0 (3.0, 7.0) | 0.400 |
SOFA | 4.0 (3.0, 9.0) | 5.0 (4.0, 11.0) | 0.334 |
Comorbidities, n (%) | |||
Hypertension | 4 (57.1) | 6 (85.7) | 0.559 |
Diabetes | 2 (28.6) | 3 (42.9) | 1.000 |
Chronic kidney disease | 1 (14.3) | 0 (0) | 1.000 |
Cancer | 1 (14.3) | 1 (14.3) | 1.000 |
Admission laboratory values | |||
WBC (× 109/L) | 8.2 (3.8, 12.9) | 19.3 (13.6, 24.8) | 0.018* |
Neutrophils (× 109/L) | 7.3 (3.8, 11.1) | 13.0 (11.7, 22.2) | 0.025* |
Lymphocytes (× 109/L) | 0.7 (0.6, 1.0) | 1.4 (0.4, 1.7) | 0.608 |
Platelets (× 109/L) | 202 (119, 225) | 212 (145, 291) | 0.565 |
Haemoglobin (g/L) | 122 (104, 137) | 123 (98, 137) | 0.898 |
Creatinine (µmol/L) | 68 (45, 184) | 65 (49, 80) | 0.609 |
p:F ratio | 124 (69, 202) | 172 (132, 304) | 0.317 |
Admission chest X-ray findings, n (%) | |||
Bilateral pneumonia | 7 (100) | 1 (14.3) | 0.005* |
Unilateral pneumonia | 0 (0) | 4 (57.1) | 0.070 |
Interstitial infiltrates | 0 (0) | 1 (14.3) | 1.000 |
Normal | 0 (0) | 1 (14.3) | 1.000 |
Sepsis diagnosis | |||
Suspected | 0 (0) | 4 (57.1) | 0.070 |
Confirmed | 7 (100) | 3 (42.9) | 0.070 |
Interventions during study | |||
Antibiotics | 7 (100) | 7 (100) | 1.000 |
Anti-virals | 3 (42.9) | 0 (0) | 0.192 |
Steroids | 1 (14.3) | 2 (28.6) | 1.000 |
Vasoactive medications | 5 (71.4) | 5 (71.4) | 1.000 |
Renal replacement therapy | 1 (14.3) | 0 (0) | 1.000 |
High-flow nasal cannula | 3 (42.9) | 1 (14.3) | 0.559 |
Non-invasive mechanical ventilation | 4 (57.1) | 7 (100) | 0.192 |
Invasive mechanical ventilation | 5 (71.4) | 6 (85.7) | 1.000 |
ICU outcome | |||
Survived | 5 (71.4) | 7 (100) | 0.462 |