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Table 1 Subject demographics and clinical data

From: Transcriptional profiling of leukocytes in critically ill COVID19 patients: implications for interferon response and coagulation

Variable COVID19 + patients COVID19– patients p-value
n 7 7 1.000
Age in years 60.0 (56.0, 67.0) 60.0 (53.0, 63.0) 0.520
Sex 5F:2 M 5F:2 M 1.000
MODS 4.0 (1.0, 7.0) 5.0 (3.0, 7.0) 0.400
SOFA 4.0 (3.0, 9.0) 5.0 (4.0, 11.0) 0.334
Comorbidities, n (%)    
 Hypertension 4 (57.1) 6 (85.7) 0.559
 Diabetes 2 (28.6) 3 (42.9) 1.000
 Chronic kidney disease 1 (14.3) 0 (0) 1.000
 Cancer 1 (14.3) 1 (14.3) 1.000
Admission laboratory values    
 WBC (× 109/L) 8.2 (3.8, 12.9) 19.3 (13.6, 24.8) 0.018*
 Neutrophils (× 109/L) 7.3 (3.8, 11.1) 13.0 (11.7, 22.2) 0.025*
 Lymphocytes (× 109/L) 0.7 (0.6, 1.0) 1.4 (0.4, 1.7) 0.608
 Platelets (× 109/L) 202 (119, 225) 212 (145, 291) 0.565
 Haemoglobin (g/L) 122 (104, 137) 123 (98, 137) 0.898
 Creatinine (µmol/L) 68 (45, 184) 65 (49, 80) 0.609
 p:F ratio 124 (69, 202) 172 (132, 304) 0.317
Admission chest X-ray findings, n (%)    
 Bilateral pneumonia 7 (100) 1 (14.3) 0.005*
 Unilateral pneumonia 0 (0) 4 (57.1) 0.070
 Interstitial infiltrates 0 (0) 1 (14.3) 1.000
 Normal 0 (0) 1 (14.3) 1.000
Sepsis diagnosis    
 Suspected 0 (0) 4 (57.1) 0.070
 Confirmed 7 (100) 3 (42.9) 0.070
Interventions during study    
 Antibiotics 7 (100) 7 (100) 1.000
 Anti-virals 3 (42.9) 0 (0) 0.192
 Steroids 1 (14.3) 2 (28.6) 1.000
 Vasoactive medications 5 (71.4) 5 (71.4) 1.000
 Renal replacement therapy 1 (14.3) 0 (0) 1.000
 High-flow nasal cannula 3 (42.9) 1 (14.3) 0.559
 Non-invasive mechanical ventilation 4 (57.1) 7 (100) 0.192
 Invasive mechanical ventilation 5 (71.4) 6 (85.7) 1.000
ICU outcome    
 Survived 5 (71.4) 7 (100) 0.462
  1. Continuous data are presented as medians (IQRs). MODS Multiple Organ Dysfunction Score, SOFA Sequential Organ Failure Assessment Score, COPD Chronic Obstructive Pulmonary Disease, WBC white blood cell