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Fig. 8 | Intensive Care Medicine Experimental

Fig. 8

From: Rapid changes in mucociliary transport in the tracheal epithelium caused by unconditioned room air or nebulized hypertonic saline and mannitol are not determined by frequency of beating cilia

Fig. 8

An example of the effect of nebulized hypertonic saline (7% NaCl) (a) and nebulized mannitol (20% Mannitol) (b) on the mean cilia beat frequency (CBF) (black) and mucus transport velocity (MTV) (grey) across the field-of-view from a video-microscopy recording shown in Additional file 2: Video S2, Additional file 3: Video S3. The shaded area represents nebulized 7% NaCl in a and nebulized 20% mannitol in b. Different regions were used for CBF analysis in a shown as a solid black line for measurements made over the entire field-of-view and a dashed line showing measurements made in a sub-region in the top left corner or the recording, since an abundance of debris prevented robust measurement in other portions of the frame

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