From: End-tidal to arterial PCO2 ratio: a bedside meter of the overall gas exchanger performance
ARDS severity | Mild | MM | MS | Severe | P |
---|---|---|---|---|---|
Number of patients | N = 33 | N = 54 | N = 70 | N = 43 | |
Age | 59.0 [43.0; 69.0] | 66.0 [53.2; 76.0] | 61.0 [45.2; 70.5] | 63.0 [52.0; 72.5] | 0.382 |
Sex | 0.905 | ||||
Female | 13 (39.4) | 16 (29.6) | 23 (32.9) | 13 (30.2) | |
Male | 20 (60.6) | 38 (70.4) | 46 (65.7) | 30 (69.8) | |
BMI | 25.6 [22.2; 28.0] | 25.0 [23.1; 27.8] | 24.2 [21.9; 26.7] | 26.1 [22.2; 32.0] | 0.107 |
SAPS II | 41.5 [27.8; 46.2] | 40.0 [31.0; 54.2] | 39.0 [33.0; 52.0] | 43.0 [35.0; 54.5] | 0.416 |
Tidal volume, ml/kg | 540 [500; 600] | 550 [480; 600] | 502 [432; 560] | 500 [428; 590] | 0.082 |
Respiratory Rate, bpm | 15.0 [12.0; 18.0] | 15.0 [13.0; 18.0] | 18.0 [14.0; 20.0] | 18.0 [15.0; 20.0] | 0.110 |
Plateau pressure, cmH2O | 19.0 [16.1; 21.3] | 17.0 [14.5; 20.0] | 18.5 [16.3; 21.0] | 18.0 [15.9; 21.0] | 0.121 |
Ers, cmH2O/L | 23.1 [17.6; 29.2] | 22.3 [19.1; 25.6] | 26.9 [21.4; 31.7] | 26.9 [21.0; 33.2] | 0.005 |
PaO2/FiO2 ratio | 230 [218; 255] | 173 [160; 183] | 122 [108; 139] | 79.6 [66.7; 87.4] | < 0.001 |
PaO2, mmHg | 96.2 [83.0; 109] | 75.2 [65.8; 81.9] | 67.2 [62.0; 71.9] | 60.0 [54.0; 71.3] | < 0.001 |
FiO2 | 0.40 [0.40; 0.45] | 0.40 [0.40; 0.50] | 0.55 [0.50; 0.60] | 0.85 [0.70; 0.92] | < 0.001 |
PaCO2, mmHg | 40.9 [38.2; 44.2] | 42.9 [38.2; 49.8] | 44.5 [39.7; 50.3] | 52.0 [43.2; 55.0] | < 0.001 |
Arterial pH | 7.39 [7.35; 7.46] | 7.39 [7.35; 7.43] | 7.38 [7.31; 7.42] | 7.36 [7.30; 7.40] | 0.024 |
ARDS causes, no. (%): | |||||
Aspiration | 1 (3.03) | 5 (9.26) | 7 (10.0) | 2 (4.65) | |
Other | 5 (15.2) | 5 (9.26) | 11 (15.7) | 5 (11.6) | |
Pneumonia | 8 (24.2) | 21 (38.9) | 35 (50.0) | 28 (65.1) | |
Sepsis | 15 (45.5) | 18 (33.3) | 14 (20.0) | 7 (16.3) | |
Trauma | 4 (12.1) | 5 (9.26) | 3 (4.29) | 0 (0.00) |