Skip to main content
Intensive Care Medicine Experimental
Fig. 5 | Intensive Care Medicine Experimental

Fig. 5

From: Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental cardiopulmonary bypass

Fig. 5

Glomerular and tubulointerstitial neutrophil infiltration and fibrin deposition. Glomerular neutrophil infiltration in rats undergoing cardiopulmonary bypass (a, CPB; grey circles, n = 13) and CPB with aprotinin treatment (b CPB + AP, red circles, n = 14) and quantified as MPO-positive cells per glomerulus (c). Glomerular fibrin deposition in rats undergoing CPB (d, grey circles, n = 10) and CPB with aprotinin treatment (e, red circles, n = 15) and quantified as red stained MSB deposits per glomerulus (f). Black arrows show representative stainings. Tubulointerstitial neutrophil infiltration in rats undergoing cardiopulmonary bypass (g, CPB; grey circles, n = 13) and CPB with aprotinin treatment (h CPB + AP, red circles, n = 14) and quantified as MPO-positive cells per glomerulus (i). Glomerular fibrin deposition in rats undergoing CPB (j, grey circles, n = 10) and CPB with aprotinin treatment (k, red circles, n = 15) and quantified as red stained MSB deposits per glomerulus (l). Black arrows show representative stainings. Data are presented as mean ± standard deviation, *p < 0.001 CPB vs. CPB + AP

Back to article page