A 29-mRNA host response test from blood accurately distinguishes bacterial and viral infections among emergency department patients

Intensive Care Medicine Experimental

Table 2 Comparison of AUROCs applying consensus vs. forced adjudications for InSep and other commonly used biomarkers

	Consensus adjudication AUROC	Forced adjudication AUROC
Bacterial vs. viral/noninfected
InSep Bacterial Score	0.94 (95% CI 0.90–0.99)	0.76 (95% CI 0.71–0.81)
PCT	0.88 (95% CI 0.79–0.96)	0.77 (95% CI 0.70–0.83)
CRP	0.80 (95% CI 0.72–0.89)	0.69 (95% CI 0.63–0.74)
WBC	0.78 (95% CI 0.69–0.87)	0.70 (95% CI 0.64–0.75)
Viral vs. bacterial/noninfected
InSep Viral Score	0.90 (95% CI 0.83–0.96)	0.70 (95% CI 0.63–0.76)