From: Induced hypernatremia in patients with moderate-to-severe ARDS: a randomized controlled study
Hypertonic saline (n = 20) | Control (n = 20) | |
---|---|---|
Age (years) | 59.5 (48.0–77.0) | 66.5 (59.0–74.5) |
Male (n,%) | 13 (65%) | 13 (65%) |
Height (cm) | 168 (165–180) | 170 (168–177) |
Weight (kg) | 80 (68–84) | 80 (70–90) |
APACHE II | 20 (15–22) | 20 (17–22) |
APACHE III | 74 (40–80) | 78 (54–87) |
APACHE III ROD | 0.25 (0.06–0.40) | 0.27 (0.08–0.51) |
CCI | 3 (0–5) | 2 (0–4) |
SOFA score | 9 (6–10) | 11 (5–13) |
Time since intubation before randomization (hours) | 12.0 (2.5–16) | 8 (3.0–20) |
CFB (ml) | 1220 (281–2340) | 899 (200–1722) |
LIS | 3.0 (2.8–3.4) | 3.0 (2.5–3.2) |
Oxygenation index (OI) | 12.4 (11.6–14.8) | 12.7 (9.6–13.4) |
ARDS Pulmonary (n,%) | 13 (65%) | 14 (70%) |
Driving pressure (cm H20) | 12 (10–13) | 12 (8–13) |
PEEP (cm H20) | 15 (12–16) | 15 (13–16) |
PaO2/FiO2 | 132 (97–154) | 140 (126–156) |
PaCO2 (mmHg) | 58 (42–69) | 61 (51–69) |
pH | 7.31 (7.21–7.41) | 7.29 (7.18–7.33) |