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Table 1 Baseline characteristics of patients included in the study

From: Induced hypernatremia in patients with moderate-to-severe ARDS: a randomized controlled study

 

Hypertonic saline

(n = 20)

Control

(n = 20)

Age (years)

59.5 (48.0–77.0)

66.5 (59.0–74.5)

Male (n,%)

13 (65%)

13 (65%)

Height (cm)

168 (165–180)

170 (168–177)

Weight (kg)

80 (68–84)

80 (70–90)

APACHE II

20 (15–22)

20 (17–22)

APACHE III

74 (40–80)

78 (54–87)

APACHE III ROD

0.25 (0.06–0.40)

0.27 (0.08–0.51)

CCI

3 (0–5)

2 (0–4)

SOFA score

9 (6–10)

11 (5–13)

Time since intubation before randomization (hours)

12.0 (2.5–16)

8 (3.0–20)

CFB (ml)

1220 (281–2340)

899 (200–1722)

LIS

3.0 (2.8–3.4)

3.0 (2.5–3.2)

Oxygenation index (OI)

12.4 (11.6–14.8)

12.7 (9.6–13.4)

ARDS Pulmonary (n,%)

13 (65%)

14 (70%)

Driving pressure (cm H20)

12 (10–13)

12 (8–13)

PEEP (cm H20)

15 (12–16)

15 (13–16)

PaO2/FiO2

132 (97–154)

140 (126–156)

PaCO2 (mmHg)

58 (42–69)

61 (51–69)

pH

7.31 (7.21–7.41)

7.29 (7.18–7.33)

  1. Data presented as Median (IQR)
  2. APACHE acute physiology and chronic health evaluation score, ROD risk of death, CCI Charlson Comorbidity Index, SOFA sequential organ failure assessment score, CFB cumulative fluid balance, LIS lung injury score, OI Oxygenation index