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Intensive Care Medicine Experimental

Table 1 Baseline characteristics

From: Rapid screening of critically ill patients for low plasma vitamin C concentrations using a point-of-care oxidation–reduction potential measurement

Patients

Dataset 2

Dataset 1a

Total (n = 25)

Total (n = 42)

Age (years)

70 (56–76)

61 (48–76)

Sex, male (%)

15 (60)

27 (64.3)

BMI (kg/m2)

26.3 (23.5–30.6)

25.3 (22.4–27.6)

SIRS/sepsis/trauma (n)

Cardiac arrest (n)

14 (56%)

11 (44%)

26 (61.9%)

16 (38.1%)

Lactate day 1 (mmol/L)

3.7 (2.4–4.9)

2.4 (1.7–4.8)

SOFA day 1b

8 ± 3

7 ± 3

APACHE II

28 (22–30)

28 (22–31)c

APACHE III

104 (71–123)

102 (73–122)

Plasma vitamin C concentration (µmol/L) day 1

28.5 (14.8–44.3)

25.3 (16.0–36.0)

sORP (mV) day 1

114.2 (98.7–131.9)

114.2 (102.2–126.9)d

Plasma vitamin C concentration (µmol/L) day 3

23.0 (12.1–53.6)e

18.7 (13.7–28.8)f

sORP (mV) day 3

121.3 (102.3–135.8)e

119.4 (107.8–135.5)g

  1. APACHE Acute Physiology and Chronic Health Evaluation; BMI body mass index; SIRS systemic inflammatory response syndrome; sORP static oxidation–reduction potential; SOFA Sequential Organ Failure Assessment
  2. Data are presented as mean ± standard deviation or as median with (interquartile range)
  3. aPreviously published data [23]. The authors gave consent for republishing the baseline characteristics
  4. bSOFA-scores are calculated without the central nervous system score due to its unreliability when patients receive sedatives. SOFA-scores were calculated according to the NICE criteria [30]
  5. cMeasured in 40 patients
  6. dMeasured in 41 patients
  7. eMeasured in 21 patients
  8. fMeasured in 36 patients
  9. gMeasured in 35 patients
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