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Intensive Care Medicine Experimental
Fig. 2 | Intensive Care Medicine Experimental

Fig. 2

From: Mortality of septic shock patients is associated with impaired mitochondrial oxidative coupling efficiency in lymphocytes: a prospective cohort study

Fig. 2

Mitochondrial bioenergetic function is reduced in lymphocytes of non-surviving septic shock patients. Variations (day 3 minus day 1 admission) in mitochondrial oxygen consumption rates in conditions not stimulated by metabolic substrates (A, ΔBasal), stimulated by complex I substrates, pyruvate, malate, and glutamate (B, ΔCI), and stimulated by complex II substrate, succinate (C, ΔCII). Figures are presented as median ± IQR. *Indicates significant differences relative to surviving at P < 0.05; **P < 0.01; and ***P < 0.001

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