Complement factor D is linked to platelet activation in human and rodent sepsis

Intensive Care Medicine Experimental

Table 4 Regression model results for in-hospital mortality in 78 patients with diagnosis sepsis or SIRS

Variables	Cox regressions model for in-hospital mortality
	Univariate models			Multivariable models
	Hazard ratio	95% CI	p value	Hazard ratio	95% CI	p value
CFD	1.13	(1.03–1.25)	0.013	1.13	(1.00–1.28)	0.043
Age	1.03	(1.00–1.06)	0.049	1.02	(0.99–1.06)	0.092
Sex	1.62	(0.78–3.36)	0.193
TAT complexes	0.99	(0.96–1.03)	0.679
D-dimer	1.02	(0.93–1.13)	0.636
Platelets	1.00	(0.99–1.00)	0.512
SOFA score	1.05	(0.91–1.21)	0.548	0.99	(0.84–1.16)	0.869
DIC score (modified)	1.22	(0.80–1.87)	0.360
Sepsis	0.89	(0.40–2.00)	0.784

Statistics: univariate and multivariable Cox regression models (linear) and derived hazard ratios (HR) and confidence intervals (CI) with a coverage of 95% of demographic and clinical variables (p < 0.05)