Fig. 3From: Interstitial washdown and vascular albumin refill during fluid infusion: novel kinetic analysis from three clinical trialsVolume kinetic analyses based on the dilution of blood Hb. The subplots in the top row show the distribution of infused fluid in volunteers between the A central and the B peripheral fluid compartment, C the excess fluid in the central compartment when analyzing the volume kinetics based on Hb minus the volume expansion as obtained when albumin was used as the marker of plasma dilution. D Return flow of fluid from the peripheral to the central space (the plasma) when contrasting the influence of high-degree versus low-degree interstitial washdown (approximately 5–95% span). Subplots E–H show the same calculations when applied to patients under general anesthesia and Subplots I–L when applied to patients with ketoacidosisBack to article page